This thesis deals with the development of guidelines for the application of the concept of Lean construction in construction companies and application of the previously mentioned guidelines in the construction management on the project of construction of a business building. At the beginning of writing this paper, the causes of time and cost overruns and poor performance of construction projects as a consequence of poor management of construction projects were identified. Also, poor application and lack of guidelines for the application of Lean construction was observed. These problems were the motivation for researching a new way of management - the concept of Lean construction and the development of guidelines for its full application, which as such do not yet exist in the literature. The next chapter provides an overview of the literature of Lean construction, through a review of the historical development of Lean production and Lean thinking, after which the basic principles and characteristics of Lean construction, as well as the tools/techniques needed for its successful application, are defined. The benefits that are realized during its implementation are listed and recognized in examples from practice that are listed in the literature. At the very end of the literature review, the most significant obstacles in the application of Lean construction and the problem of the lack of clear guidelines for its application were highlighted. After gathering knowledge about Lean construction from the literature review, guidelines for the application of this concept were developed. The guidelines are structured in three subcategories – barriers to implementation of Lean construction and suggestions for their mitigation, a flow chart of steps for implementing Lean construction divided into three phases from the contractor's perspective, and key success factors for implementing the Lean concept. In the last part of the paper, after the definition of the guidelines, the case study of the project for the construction of a business – operational building in the Republic of Croatia was analyzed. For research purposes, some time was spent on the construction site to identify the degree of application of the proposed guidelines in the project. The application of Lean construction in the observed construction company is described in detail together with the characteristics of the observed project and the implementation of each step from the flow chart for the application of Lean construction with the described method of application of each tool, as well as perceived benefits and obstacles. Techniques and key success factors for the application of Lean construction have been identified. The discussion chapter briefly describes the additional possibilities that could be implemented in the observed project and offers a recapitulation of the whole paper