Prepress plays an important role in the quality of reproduction of information and it has to be adapted to variety of conditions and media. In order to have well prepared files, it is necessary to know the laws that are specific to individual media. It is well known that the prepress is not the same for print and Internet, as well as page layout. This thesis will explain the specifications related to this theme and customize prepress and preparation for Internet and print while providing guidelines that would ensure the quality of information. The theoretical part of the paper explains the specifics of preparing for various media, such as print and Internet, with a focus on colour reproduction and image, typography and layout. Experimental work is based on research conducted for the purpose of adjusting the preparation of materials for print and the Internet, and achieving optimal quality of prepress and thus reproduction. The research is conducted on the basis of several solutions of layout for brochure and website of the same content, following the specifics of each media. Parameters that would provide quality of the preparatory process for print and Internet are proposed after the research and analyzed results.