Tomić, D. (2021). Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein [Data set]. https://urn.nsk.hr/urn:nbn:hr:241:733364.
Tomić, Draško. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. Institut Ruđer Bošković, 2021. 17 Jul 2024. https://urn.nsk.hr/urn:nbn:hr:241:733364.
Tomić, Draško. 2021. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. Institut Ruđer Bošković. https://urn.nsk.hr/urn:nbn:hr:241:733364.
Tomić, D. 2021. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. Institut Ruđer Bošković. [Online]. [Accessed 17 July 2024]. Available from: https://urn.nsk.hr/urn:nbn:hr:241:733364.
Tomić D. Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein. [Internet]. Institut Ruđer Bošković: , HR; 2021, [cited 2024 July 17] Available from: https://urn.nsk.hr/urn:nbn:hr:241:733364.
D. Tomić, Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein, Institut Ruđer Bošković, 2021. Accessed on: Jul 17, 2024. Available: https://urn.nsk.hr/urn:nbn:hr:241:733364.
Title (english)
Results of the efficacy of FDA approved antiviral drugs on SARS-CoV-2 spike glycoprotein
Author
Draško Tomić Institut Ruđer Bošković Ruđer Bošković Institute
Scientific / art field, discipline and subdiscipline
BIOMEDICINE AND HEALTHCARE Basic Medical Sciences Human Genetics, Genomics and Proteomics
Scientific / art field, discipline and subdiscipline
BIOMEDICINE AND HEALTHCARE Pharmacy Medical Biochemistry
Scientific / art field, discipline and subdiscipline
These results were obtained using the Vini in silico model of cancer in the period from March to December 2020. The efficacy of 49 FDA-approved antiviral drugs on SARS-CoV-2 spike glycoprotein was analyzed. Based on the fact that HIV drugs showed the highest efficacy, the efficacy of their double and triple combinations was further calculated.
Methods (english)
These results were obtained using the Vini in silico model of cancer in the period from March to December 2020. The efficacy of 49 FDA-approved antiviral drugs on SARS-CoV-2 spike glycoprotein has analyzed with the Vini in silico model of cancer. Based on the fact that HIV drugs showed the highest efficacy, the efficacy of their double and triple combinations was further calculated. Finally, 10 most effective HIV drug combinations were finally examined on their possible adverse effects with Medscape and Lexicomp software.
Number: KK.01.1.1.01.009 Title (croatian): Napredne metode i tehnologije u znanosti o podatcima i kooperativnim sustavima-DATACROSS Acronym: DATACROSS Leader: Sven Lončarić; Petrović Ivan Jurisdiction: eu