prikaz prve stranice dokumenta Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers
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Scientific paper - Original scientific paper
Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers
COPD: Journal of Chronic Obstructive Pulmonary Disease, 13 (2016), 6; 741-749. https://doi.org/10.3109/15412555.2016.1164129
Labor, Marina; Vrbica, Žarko; Gudelj, Ivan; Labor, Slavica; Jurić, Iva; Plavec, Davor

Institutional repository: Repository UHC Osijek

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Labor, M., Vrbica, Ž., Gudelj, I., Labor, S., Jurić, I. & Plavec, D. (2016). Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers. COPD: Journal of Chronic Obstructive Pulmonary Disease, 13. (6), 741-749. doi: 10.3109/15412555.2016.1164129

Labor, Marina, et al. "Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers." COPD: Journal of Chronic Obstructive Pulmonary Disease, vol. 13, no. 6, 2016, pp. 741-749. https://doi.org/10.3109/15412555.2016.1164129

Labor, Marina, Žarko Vrbica, Ivan Gudelj, Slavica Labor, Iva Jurić and Davor Plavec. "Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers." COPD: Journal of Chronic Obstructive Pulmonary Disease 13, no. 6 (2016): 741-749. https://doi.org/10.3109/15412555.2016.1164129

Labor, M., et al. (2016) 'Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers', COPD: Journal of Chronic Obstructive Pulmonary Disease, 13(6), pp. 741-749. doi: 10.3109/15412555.2016.1164129

Labor M, Vrbica Ž, Gudelj I, Labor S, Jurić I, Plavec D. Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers. COPD: Journal of Chronic Obstructive Pulmonary Disease [Internet]. 2016 [cited 2024 December 18];13(6):741-749. doi: 10.3109/15412555.2016.1164129

M. Labor, Ž. Vrbica, I. Gudelj, S. Labor, I. Jurić and D. Plavec, "Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers", COPD: Journal of Chronic Obstructive Pulmonary Disease, vol. 13, no. 6, pp. 741-749, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:141036. [Accessed: 18 December 2024]

Metadata
Title (english)Exhaled Breath Temperature as a Novel Marker of Future Development of COPD: Results of a Follow-up Study in Smokers
AuthorMarina Labor
MBZ: 357633
AuthorŽarko Vrbica
MBZ: 259013
AuthorIvan Gudelj
AuthorSlavica Labor
MBZ: 330076
AuthorIva Jurić
AuthorDavor Plavec
MBZ: 159962
Author's institutionUniversity of Dubrovnik
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Although only less than one-third of smokers develop COPD, early marker(s) of COPD development are lacking. The aim of this research was to assess the ability of an average equilibrium exhaled breath temperature (EBT) in identifying susceptibility to cigarette smoke so as to predict COPD development in smokers at risk. The study was a part of a multicenter prospective cohort study in current smokers (N = 140, both sexes, 40-65 years, ≥20 pack-years) with no prior diagnosis of COPD. Diagnostic workup includes history, physical, quality of life, hematology and highly sensitive CRP, EBT before and after smoking a cigarette, lung function with bronchodilator test, and 6-minute walk test. Patients without a diagnosis of COPD and in GOLD 1 stage at initial assessment were reassessed after 2 years. COPD was additionally diagnosed based on lower level of normal (LLN) lung function criteria. Utility of EBT for disease progression was analyzed using receiver operator curve (ROC) and logistic regression analyses. Change in EBT after smoking a cigarette at initial visit (ΔEBT) was significantly predictive for disease progression (newly diagnosed COPD; newly diagnosed COPD + severity progression) after 2 years (p < 0.05 for both). ΔEBT had an AUC of 0.859 (p = 0.011) with sensitivity of 66.7% and specificity of 98.1% for newly diagnosed COPD using LLN criteria. We conclude that EBT shows potential for predicting the future development of COPD in current smokers. This was best seen using LLN to diagnose COPD, adding further evidence to question the use of GOLD criteria for diagnosing COPD.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCOPD: Journal of Chronic Obstructive Pulmonary Disease
Numberingvol. 13, no. 6, pp. 741-749
p-ISSN1541-2555
e-ISSN1541-2563
DOIhttps://doi.org/10.3109/15412555.2016.1164129
URN:NBNurn:nbn:hr:239:141036
Publication2016
Document URLhttps://www.tandfonline.com/doi/full/10.3109/15412555.2016.1164129
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 3.0 Unported (CC BY 3.0) icon
Created on2019-10-29 12:49:50