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Scientific paper - Original scientific paper
Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study
Rheumatology International, 35 (2015), 12; 2047-2057. https://doi.org/10.1007/s00296-015-3307-0
Šalamon, Lea; Morović Vergles, Jadranka; Marasović Krstulović, Daniela; Kehler, Tatjana; Šakić, Davorin; Badovinac, Olga; Vlak, Tonko; Novak, Srđan; Štiglić Rogoznica, Nives; Hanih, Marino; Bedeković, Dražen; Grazio, Simeon; Kadojić, Mira; Milas Ahić, Jasminka; Prus, Višnja; Stamenković, Doris; Šošo, Daniela; Anić, Branimir; Babić Naglić, Ðurđica; Gamulin, Stjepan More authors...

Institutional repository: Repository UHC Osijek

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Šalamon, L., Morović Vergles, J., Marasović Krstulović, D., Kehler, T., Šakić, D., Badovinac, O. ... Gamulin, S. (2015). Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study. Rheumatology International, 35. (12), 2047-2057. doi: 10.1007/s00296-015-3307-0

Šalamon, Lea, et al. "Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study." Rheumatology International, vol. 35, no. 12, 2015, pp. 2047-2057. https://doi.org/10.1007/s00296-015-3307-0

Šalamon, Lea, Jadranka Morović Vergles, Daniela Marasović Krstulović, Tatjana Kehler, Davorin Šakić, Olga Badovinac, Tonko Vlak, et al. "Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study." Rheumatology International 35, no. 12 (2015): 2047-2057. https://doi.org/10.1007/s00296-015-3307-0

Šalamon, L., et al. (2015) 'Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study', Rheumatology International, 35(12), pp. 2047-2057. doi: 10.1007/s00296-015-3307-0

Šalamon L, Morović Vergles J, Marasović Krstulović D, Kehler T, Šakić D, Badovinac O, and sur.. Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study. Rheumatology International [Internet]. 2015 [cited 2024 November 22];35(12):2047-2057. doi: 10.1007/s00296-015-3307-0

L. Šalamon, et al., "Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study", Rheumatology International, vol. 35, no. 12, pp. 2047-2057, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:951547. [Accessed: 22 November 2024]

Metadata
Title (english)Differences in the Prevalence and Characteristics of Metabolic Syndrome in Rheumatoid Arthritis and Osteoarthritis: a Multicentric Study
AuthorLea Šalamon
AuthorJadranka Morović Vergles
MBZ: 140933
AuthorDaniela Marasović Krstulović
MBZ: 341183
AuthorTatjana Kehler
MBZ: 280380
AuthorDavorin Šakić
MBZ: 182392
AuthorOlga Badovinac
AuthorTonko Vlak
MBZ: 193776
AuthorSrđan Novak
AuthorNives Štiglić Rogoznica
AuthorMarino Hanih
AuthorDražen Bedeković
AuthorSimeon Grazio
MBZ: 178772
AuthorMira Kadojić
MBZ: 240403
AuthorJasminka Milas Ahić
MBZ: 288280
AuthorVišnja Prus
MBZ: 333013
AuthorDoris Stamenković
AuthorDaniela Šošo
AuthorBranimir Anić
MBZ: 140514
AuthorÐurđica Babić Naglić
AuthorStjepan Gamulin
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The purpose of the study was to examine whether rheumatoid arthritis (RA) patients have higher prevalence of metabolic syndrome (MetS) than osteoarthritis (OA) patients in association with a higher level of chronic systemic inflammation in rheumatoid arthritis. A total of 583 RA and 344 OA outpatients were analyzed in this multicentric study. Metabolic syndrome was defined using the National Cholesterol Education Program Adult Treatment Panel III criteria. A 1.6-fold higher prevalence of MetS was found in patients with OA compared with the RA patients. Among the parameters of MetS, patients with OA had significantly higher levels of waist circumference, systolic blood pressure, fasting blood glucose and triglycerides, whereas HDL cholesterol and diastolic blood pressure values were similar in both groups of patients. Higher values of inflammatory markers [C-reactive protein (CRP), erythrocyte sedimentation rate (ESR)] in MetS than in non-MetS patients and higher prevalence of MetS in patients with CRP level ≥5 mg/L in both RA and OA patients were found. In multivariate logistic regression analysis, significant predictors of MetS were type of arthritis (OA vs. RA; OR 2.5 [95 % CI 1.82-3.43]), age (OR 1.04 [95 % CI 1.03-1.06]) and ESR (OR 1.01; [95 % CI 1.00-1.01]). The significant association between OA and MetS was maintained in the regression model that controlled for body mass index (OR 1.87 [95 % CI 1.34-2.61]). The present analysis suggests that OA is associated with an increased risk of MetS, which may be due to a common underlying pathogenic mechanism.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleRheumatology International
Numberingvol. 35, no. 12, pp. 2047-2057
p-ISSN0172-8172
e-ISSN1437-160X
DOIhttps://doi.org/10.1007/s00296-015-3307-0
URN:NBNurn:nbn:hr:239:951547
Publication2015
Document URLhttps://link.springer.com/article/10.1007/s00296-015-3307-0
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2019-11-04 08:27:06