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Scientific paper - Original scientific paper
Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice
Somatosensory and Motor Research, 25 (2008), 3; 163-170. https://doi.org/10.1080/08990220802276666
Pavić, Roman; Pavić, Michele L.; Tot, Ozana Katarina; Benšić, Mirta; Heffer-Lauc, Marija

Institutional repository: Repository UHC Osijek

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Pavić, R., Pavić, M. L., Tot, O. K., Benšić, M. & Heffer Lauc, M. (2008). Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice. Somatosensory and Motor Research, 25. (3), 163-170. doi: 10.1080/08990220802276666

Pavić, Roman, et al. "Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice." Somatosensory and Motor Research, vol. 25, no. 3, 2008, pp. 163-170. https://doi.org/10.1080/08990220802276666

Pavić, Roman, Michele L. Pavić, Ozana Katarina Tot, Mirta Benšić and Marija Heffer Lauc. "Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice." Somatosensory and Motor Research 25, no. 3 (2008): 163-170. https://doi.org/10.1080/08990220802276666

Pavić, R., et al. (2008) 'Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice', Somatosensory and Motor Research, 25(3), pp. 163-170. doi: 10.1080/08990220802276666

Pavić R, Pavić ML, Tot OK, Benšić M, Heffer Lauc M. Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice. Somatosensory and Motor Research [Internet]. 2008 [cited 2024 November 24];25(3):163-170. doi: 10.1080/08990220802276666

R. Pavić, M. L. Pavić, O. K. Tot, M. Benšić and M. Heffer Lauc, "Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice", Somatosensory and Motor Research, vol. 25, no. 3, pp. 163-170, 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:023836. [Accessed: 24 November 2024]

Metadata
Title (english)Side Distinct Sciatic Nerve Recovery Differences Between Rats and Mice
AuthorRoman Pavić
MBZ: 285214
AuthorMichele L. Pavić
AuthorOzana Katarina Tot
MBZ: 344381
AuthorMirta Benšić
MBZ: 145672
AuthorMarija Heffer-Lauc
MBZ: 178985
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
The Sciatic Functional Index (SFI) is widely used to evaluate functional recovery after sciatic nerve injury, primarily in the rat, and more recently shown useful in the mouse. This quantitative, non-invasive method allows tracking of regeneration capability, visible in the gait of the animal. Using a Martin micro needle holder, carrying a force measured to be 49.2 N, the left sciatic nerve was crushed for 60 s. We accumulated data from walking tracks collected preoperatively and 1, 7, 14, 21, and 28 days after injury. SFI values were first calculated in the traditional manner. Then using the preoperative values as the normal value in the postoperative calculations, SFI was again calculated; this isolated the calculations to either injured or contra lateral leg giving a ‘‘split’’ plot. The traditional SFI calculations resulted in typical shaped graphs for both rats and mice. However, the ‘‘split’’ SFI calculations showed how rats and mice differ in their recovery from sciatic nerve injury. The mouse graph shows the intact leg remaining stable and the injured leg having functional impairment, which then recovers. The rat graph showed functional impairment of the injured leg, however, the intact leg had an increase in SFI values as if to compensate until the injured leg showed recovery.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleSomatosensory and Motor Research
Numberingvol. 25, no. 3, pp. 163-170
p-ISSN0899-0220
e-ISSN1369-1651
DOIhttps://doi.org/10.1080/08990220802276666
URN:NBNurn:nbn:hr:239:023836
Publication2008
Document URLhttps://www.tandfonline.com/doi/full/10.1080/08990220802276666
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-03-27 09:52:20