prikaz prve stranice dokumenta Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients
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Scientific paper - Original scientific paper
Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients
European Archives of Oto-Rhino-Laryngology, 272 (2015), 11; 3539-3544. https://doi.org/10.1007/s00405-014-3396-5
Rosso, Marinela; Prgomet, Drago; Marjanović, Ksenija; Pušeljić, Silvija; Kraljik, Nikola

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Rosso, M., Prgomet, D., Marjanović, K., Pušeljić, S. & Kraljik, N. (2015). Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients. European Archives of Oto-Rhino-Laryngology, 272. (11), 3539-3544. doi: 10.1007/s00405-014-3396-5

Rosso, Marinela, et al. "Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients." European Archives of Oto-Rhino-Laryngology, vol. 272, no. 11, 2015, pp. 3539-3544. https://doi.org/10.1007/s00405-014-3396-5

Rosso, Marinela, Drago Prgomet, Ksenija Marjanović, Silvija Pušeljić and Nikola Kraljik. "Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients." European Archives of Oto-Rhino-Laryngology 272, no. 11 (2015): 3539-3544. https://doi.org/10.1007/s00405-014-3396-5

Rosso, M., et al. (2015) 'Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients', European Archives of Oto-Rhino-Laryngology, 272(11), pp. 3539-3544. doi: 10.1007/s00405-014-3396-5

Rosso M, Prgomet D, Marjanović K, Pušeljić S, Kraljik N. Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients. European Archives of Oto-Rhino-Laryngology [Internet]. 2015 [cited 2024 December 24];272(11):3539-3544. doi: 10.1007/s00405-014-3396-5

M. Rosso, D. Prgomet, K. Marjanović, S. Pušeljić and N. Kraljik, "Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients", European Archives of Oto-Rhino-Laryngology, vol. 272, no. 11, pp. 3539-3544, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:470411. [Accessed: 24 December 2024]

Metadata
Title (english)Pathohistological Changes of Tracheal Epithelium in Laryngectomized Patients
AuthorMarinela Rosso
MBZ: 357681
AuthorDrago Prgomet
MBZ: 201905
AuthorKsenija Marjanović
MBZ: 344392
AuthorSilvija Pušeljić
MBZ: 263190
AuthorNikola Kraljik
Author's institution(Clinical hospital center Osijek)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Physical Medicine and Rehabilitation
Abstract (english)
Abstract Total laryngectomy results in a permanent disconnection of the upper and lower airways. Thus, the upper airways are bypassed and can no longer condition, humidify, and filter the inhaled air, leading to damage of the tracheobronchial epithelium. There is little scientific information available about the effects of tracheostoma breathing and the degree of mucosal damage in laryngectomized patients. The aims of this study were to determine the histopathologic findings and investigate the potential impact of using a heat and moisture exchanger (HME) on the tracheal epithelium in long-term tracheostomy patients. Tracheal mucosal biopsies were taken from a total of 70 patients. Specimens were stained with hematoxylin and eosin and examined by a light microscope. Normal pseudostratified ciliated columnar epithelium was found in only 9 (12.9 %) cases; while, 17 (24.3 %) cases had some degree of basal cell hyperplasia. Squamous metaplasia was the most common finding (50 %). Pre-invasive lesions (mild and moderate squamous dysplasia) were found in only one patient who used an HME, and in eight (11.4 %) non-users. Although the HME cannot completely restore the physiological functions of the upper respiratory track, it delivers a better quality of air to the lower airways and has a positive effect on tracheal mucosa.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleEuropean Archives of Oto-Rhino-Laryngology
Numberingvol. 272, no. 11, pp. 3539-3544
p-ISSN0937-4477
e-ISSN1434-4726
DOIhttps://doi.org/10.1007/s00405-014-3396-5
URN:NBNurn:nbn:hr:239:470411
Publication2015
Document URLhttps://link.springer.com/article/10.1007%2Fs00405-014-3396-5
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-03-31 08:42:43