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Professional paper - Review paper
Diuretici – puno više od terapije edema
Medicus, 25 (2016), 2; 139-143. urn:nbn:hr:239:443642
Selthofer-Relatić, Kristina

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Selthofer Relatić, K. (2016). Diuretici – puno više od terapije edema. Medicus, 25. (2), 139-143. Retrieved from https://urn.nsk.hr/urn:nbn:hr:239:443642

Selthofer Relatić, Kristina. "Diuretici – puno više od terapije edema." Medicus, vol. 25, no. 2, 2016, pp. 139-143. https://urn.nsk.hr/urn:nbn:hr:239:443642

Selthofer Relatić, Kristina. "Diuretici – puno više od terapije edema." Medicus 25, no. 2 (2016): 139-143. https://urn.nsk.hr/urn:nbn:hr:239:443642

Selthofer Relatić, K. (2016) 'Diuretici – puno više od terapije edema', Medicus, 25(2), pp. 139-143. Available at: https://urn.nsk.hr/urn:nbn:hr:239:443642 (Accessed 21 November 2024)

Selthofer Relatić K. Diuretici – puno više od terapije edema. Medicus [Internet]. 2016 [cited 2024 November 21];25(2):139-143. Available at: https://urn.nsk.hr/urn:nbn:hr:239:443642

K. Selthofer Relatić, "Diuretici – puno više od terapije edema", Medicus, vol. 25, no. 2, pp. 139-143, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:443642. [Accessed: 21 November 2024]

Metadata
Title (croatian)Diuretici – puno više od terapije edema
Title (english)Diuretics – More Than Just Treatment for Oedema
AuthorKristina Selthofer-Relatić
MBZ: 333024
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (croatian)
Diuretici su dugi niz godina prisutni kao lijekovi za liječenje arterijske hipertenzije i simptomatska terapija srčanog zatajivanja. Tijekom proteklih godina pozicija diuretika u navedenim indikacijama dodatno je analizirana pa je temeljem brojnih studija zaključeno da je opravdana primjena tiazidskih diuretika u monoterapiji i u kombinacijama s drugim skupinama antihipertenziva kao vodeće skupine lijekova u liječenju hipertenzije, prevenciji moždanog udara, hipertenzivnoga srčanog zatajivanja te kod osoba starije životne dobi. Diuretici Henleove petlje i dalje su temelj terapije akutnog i kroničnoga srčanog zatajivanja, dok su novija istraživanja pozicionirala selektivne blokatore mineralokortikoidnih receptora u liječenju kroničnoga srčanog zatajivanja s utjecajem na tijek kardiovaskularnih ishoda. Lijekovi iz skupine osmotskih diuretika koji blokiraju glukoza / natrij kotransporter 2 (SGLT2) izazivajući glukozuriju efikasno snižavaju hiperglikemiju i HbA1c te su dio moderne terapije šećerne bolesti tipa 2 s mogućim dodatnim pozitivnim učincima u redukciji kardiovaskularnih neželjenih događaja.
Abstract (english)
Diuretics have been present for many years as drugs for the treatment of arterial hypertension and as a symptomatic treatment of heart failure. Over the years, the position of diuretics for these indications has further been analysed. Numerous studies have shown that it is justified to use the thiazide diuretic as monotherapy and in combination with other antihypertensive drugs, as the leading group in the treatment of hypertension, stroke prevention, hypertensive heart failure and in the elderly. Loop diuretics remain the cornerstone of treating acute and chronic heart failure, while recent research has positioned selective mineralocorticoid receptor blockers in the treatment of chronic heart failure with an impact on the course of cardiovascular outcomes. Osmotic diuretics that block glucose / sodium cotransporter 2 (SGLT2) causing glucosuria and effectively reducing hyperglycemia and HbA1c are a part of modern therapy of type 2 diabetes mellitus with additional positive effects in the reduction of cardiovascular adverse events.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedicus
Numberingvol. 25, no. 2, pp. 139-143
p-ISSN1330-013X
e-ISSN1848-8315
URN:NBNurn:nbn:hr:239:443642
Publication2016
Document URLhttps://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=250805
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2019-09-16 06:53:44