prikaz prve stranice dokumenta Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation
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Scientific paper - Original scientific paper
Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation
Croatian medical journal, 58 (2017), 6; 395-405. https://doi.org/10.3325/cmj.2017.58.395
Pavlisa, Gordana; Labor, Marina; Puretic, Hrvoje; Hećimović, Ana; Jakopović, Marko; Samaržija, Miroslav

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Pavlisa, G., Labor, M., Puretic, H., Hećimović, A., Jakopović, M. & Samaržija, M. (2017). Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation. Croatian medical journal, 58. (6), 395-405. doi: 10.3325/cmj.2017.58.395

Pavlisa, Gordana, et al. "Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation." Croatian medical journal, vol. 58, no. 6, 2017, pp. 395-405. https://doi.org/10.3325/cmj.2017.58.395

Pavlisa, Gordana, Marina Labor, Hrvoje Puretic, Ana Hećimović, Marko Jakopović and Miroslav Samaržija. "Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation." Croatian medical journal 58, no. 6 (2017): 395-405. https://doi.org/10.3325/cmj.2017.58.395

Pavlisa, G., et al. (2017) 'Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation', Croatian medical journal, 58(6), pp. 395-405. doi: 10.3325/cmj.2017.58.395

Pavlisa G, Labor M, Puretic H, Hećimović A, Jakopović M, Samaržija M. Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation. Croatian medical journal [Internet]. 2017 [cited 2024 November 22];58(6):395-405. doi: 10.3325/cmj.2017.58.395

G. Pavlisa, M. Labor, H. Puretic, A. Hećimović, M. Jakopović and M. Samaržija, "Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation", Croatian medical journal, vol. 58, no. 6, pp. 395-405, 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:239:860733. [Accessed: 22 November 2024]

Metadata
Title (english)Anemia, Hypoalbuminemia, and Elevated Troponin Levels as Risk Factors for Respiratory Failure in Patients With Severe Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Invasive Mechanical Ventilation
AuthorGordana Pavlisa
MBZ: 261252
AuthorMarina Labor
MBZ: 357633
AuthorHrvoje Puretic
AuthorAna Hećimović
MBZ: 217216
AuthorMarko Jakopović
MBZ: 278365
AuthorMiroslav Samaržija
MBZ: 146943
Author's institution(Clinical hospital center Osijek)
Author's institutionJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Biochemistry and Molecular Biology
Abstract (english)
Aim: to determine in-hospital and post-discharge mortality, readmission rates, and predictors of invasive mechanical ventilation (IMV) in patients treated at intensive care unit (ICU) due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Methods: a retrospective observational cohort study included all patients treated at a respiratory ICU for AECOPD during one year. A total of 62 patients (41 men) with mean age 68.4 ± 10.4 years were analyzed for outcomes including in-hospital and post-discharge mortality, readmission rates, and IMV. Patients’ demographic, hematologic, biochemical data and arterial blood gas (ABG) values were recorded on admission to hospital. Mean duration of followup time was 2.4 years. Results: of 62 patients, 7 (11.3%) died during incident hospitalization and 21 (33.9%) died during the follow-up. The overall 2.4-year mortality was 45.2%. Twenty nine (46.8%) patients were readmitted due to AECOPD. The average number of readmissions was 1.2. Multivariate analysis showed that blood pH, bicarbonate levels, low albumin, low serum chloride, and low hemoglobin were significant predictors of IMV during incident hospitalization (P < 0.001 for the overall model fit). Conclusion: high in-hospital and post-discharge mortality and high readmission rates in our patients treated due to AECOPD at ICU indicate that these patients represent a high risk group in need of close monitoring. Our results suggested that anemia, hypoalbuminemia, and elevated troponin levels were risk factors for the need of IMV in severe AECOPD. Identification of such high-risk patients could provide the opportunity for administration of an appropriate and timely treatment.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCroatian medical journal
Numberingvol. 58, no. 6, pp. 395-405
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2017.58.395
URN:NBNurn:nbn:hr:239:860733
Publication2017
Document URLhttps://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=294825
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-09-16 11:58:52