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Professional paper - Professional paper
Treatment of Venous Thromboembolism during Pregnancy and Puerperium
Acta clinica Croatica, 45 (2006), 1; 31-35. urn:nbn:hr:220:019548
Gaćina, Petar; Čaržavec, Dubravka; Stančić, Vladimir; Pejša, Vlatko

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Gaćina, P., Čaržavec, D., Stančić, V. & Pejša, V. (2006). Treatment of Venous Thromboembolism during Pregnancy and Puerperium. Acta clinica Croatica, 45. (1), 31-35. Retrieved from https://urn.nsk.hr/urn:nbn:hr:220:019548

Gaćina, Petar, et al. "Treatment of Venous Thromboembolism during Pregnancy and Puerperium." Acta clinica Croatica, vol. 45, no. 1, 2006, pp. 31-35. https://urn.nsk.hr/urn:nbn:hr:220:019548

Gaćina, Petar, Dubravka Čaržavec, Vladimir Stančić and Vlatko Pejša. "Treatment of Venous Thromboembolism during Pregnancy and Puerperium." Acta clinica Croatica 45, no. 1 (2006): 31-35. https://urn.nsk.hr/urn:nbn:hr:220:019548

Gaćina, P., et al. (2006) 'Treatment of Venous Thromboembolism during Pregnancy and Puerperium', Acta clinica Croatica, 45(1), pp. 31-35. Available at: https://urn.nsk.hr/urn:nbn:hr:220:019548 (Accessed 26 November 2024)

Gaćina P, Čaržavec D, Stančić V, Pejša V. Treatment of Venous Thromboembolism during Pregnancy and Puerperium. Acta clinica Croatica [Internet]. 2006 [cited 2024 November 26];45(1):31-35. Available at: https://urn.nsk.hr/urn:nbn:hr:220:019548

P. Gaćina, D. Čaržavec, V. Stančić and V. Pejša, "Treatment of Venous Thromboembolism during Pregnancy and Puerperium", Acta clinica Croatica, vol. 45, no. 1, pp. 31-35, 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:019548. [Accessed: 26 November 2024]

Metadata
Title (english)Treatment of Venous Thromboembolism during Pregnancy and Puerperium
Title (croatian)Liječenje venske tromboembolije za vrijeme trudnoće i babinja
AuthorPetar Gaćina
AuthorDubravka Čaržavec
AuthorVladimir Stančić
AuthorVlatko Pejša
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Venous thromboembolism (VTE) occurs infrequently but remains the leading cause of pregnancy- and puerperium-related mortality in industrialized countries. In pregnant women, the risk of VTE is about 4- to 5-fold that in non-pregnant women. The pathogenesis of VTE is associated with venous stasis, endothelial damage to pelvic veins at delivery, and procoagulant changes that occur during pregnancy and puerperium. The most common risk factors for VTE during pregnancy and puerperium are previous thrombotic event(s), thrombophilia, age over 35, obesity and operative delivery. Deep venous thrombosis in pregnancy and puerperium is usually left-sided (85% versus 55% in non-pregnant patients) and iliofemoral (72% in pregnancy versus 9% in non-pregnant patients). Low-molecular weight heparins (LMWHs) are the drugs of choice for the treatment of VTE during pregnancy and puerperium, as they are effective and have substantially fewer side effects such as heparin-induced thrombocytopenia, bleeding and osteoporosis as well as more reliable antithrombotic activity compared with unfractionated heparin.
Abstract (croatian)
Venska tromboembolija (VTE) nije učestala, ali ostaje vodećim uzrokom smrtnosti za vrijeme trudnoće i babinja u razvijenim zemljama. Rizik VTE je oko 4-5 puta veći u trudnica nego u žena iste dobi bez trudnoće. Nastanak VTE je povezan s venskom stazom, oštećenjem endotela vena zdjelice uslijed poroda, te povećanom sklonošću zgrušavanju krvi za vrijeme trudnoće i babinja. Najčešći rizični čimbenici VTE za vrijeme trudnoće i babinja su prethodna tromboza(e), nasljedna sklonost trombozi, trudnice starije od 35 godina, debljina i porod operacijskim zahvatom. Duboka venska tromboza za vrijeme trudnoće i babinja je češće lijevostrana (85% nasuprot 55% u žena iste dobi koje nisu trudne) i iliofemoralna (72% u trudnica nasuprot 9%). Heparini male molekularne težine su lijekovi izbora u liječenju VTE za vrijeme trudnoće i babinja, jer su djelotvorni i imaju znatno manje nuspojava, kao trombocitopeniju potaknutu heparinom, krvarenje i osteoporozu te pouzdaniju protutrombotsku aktivnost u odnosu na nefrakcionirani heparin.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 45, no. 1, pp. 31-35
p-ISSN0353-9466
e-ISSN1333-9451
URN:NBNurn:nbn:hr:220:019548
Publication2006
Document URLhttps://hrcak.srce.hr/14047
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2023-06-13 12:09:45