prikaz prve stranice dokumenta Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia
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Scientific paper - Original scientific paper
Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia
Human Psychopharmacology: Clinical and Experimental, 36 (2020); e2763. https://doi.org/10.1002/hup.2763
Karlović, Dalibor; Silić, Ante; Crnković, Danijel; Peitl, Vjekoslav

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Karlović, D., Silić, A., Crnković, D. & Peitl, V. (2020). Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia. Human Psychopharmacology: Clinical and Experimental, 36.. doi: 10.1002/hup.2763

Karlović, Dalibor, et al. "Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia." Human Psychopharmacology: Clinical and Experimental, vol. 36, 2020. https://doi.org/10.1002/hup.2763

Karlović, Dalibor, Ante Silić, Danijel Crnković and Vjekoslav Peitl. "Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia." Human Psychopharmacology: Clinical and Experimental 36 (2020). https://doi.org/10.1002/hup.2763

Karlović, D., et al. (2020) 'Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia', Human Psychopharmacology: Clinical and Experimental, 36. doi: 10.1002/hup.2763

Karlović D, Silić A, Crnković D, Peitl V. Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia. Human Psychopharmacology: Clinical and Experimental [Internet]. 2020 [cited 2024 May 02];36. doi: 10.1002/hup.2763

D. Karlović, A. Silić, D. Crnković and V. Peitl, "Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia", Human Psychopharmacology: Clinical and Experimental, vol. 36, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:526967. [Accessed: 02 May 2024]

Metadata
Title (english)Effects of aripiprazole long‐acting injectable antipsychotic on hospitalization in recent‐onset schizophrenia
AuthorDalibor Karlović
AuthorAnte Silić
AuthorDanijel Crnković
AuthorVjekoslav Peitl
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Psychiatry
Abstract (english)
Objective: Recent‐onset schizophrenia (ROS) represents a critical period that can greatly influence the clinical course of schizophrenia. The use of long‐acting injectable antipsychotics (LAIs) in this period is increasingly being considered as a first‐line treatment option. Aripiprazole LAI (ALAI) is the newest of all LAI's available on the market, with limited data on its effects on hospitalization rates after first episode of schizophrenia. It was our goal to evaluate whether ALAI has an effect on hospitalization rates, number of bed days and clinical improvement in patients with ROS. Methods: This mirror‐image study included 138 inpatients suffering from schizophrenia. We collected sociodemographic data on all individuals, number of hospitalization days, hospitalization rates as well as Clinical Global Impression Scale—severity of illness (CGI‐S) and Clinician‐Rated Dimensions of Psychosis Symptom Severity (CRDPSS) scores at the initiation of ALAI and at the end of a 1 year follow up. Results: Mean number of hospitalizations and hospitalization days in the year after starting ALAI significantly decreased compared to the year before (p ¼ 0.005 and p < 0.001). Mean scores on both CGI and CRDPSS also significantly decreased after initiating ALAI (p < 0.001). Conclusion: Results suggest that ALAI is an important therapeutic option in patients with ROS. It leads to reduced usage of hospital services, potentially reducing the socio‐economic healthcare burden.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleHuman Psychopharmacology: Clinical and Experimental
Numberingvol. 36, e2763
p-ISSN0885-6222
e-ISSN1099-1077
DOIhttps://doi.org/10.1002/hup.2763
URN:NBNurn:nbn:hr:220:526967
Publication2020
Document URLhttps://onlinelibrary.wiley.com/doi/10.1002/hup.2763
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2023-09-29 08:17:19