prikaz prve stranice dokumenta Malignant transformation of grade II ganglioglioma to glioblastoma: A case report
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Scientific paper - Case study
Malignant transformation of grade II ganglioglioma to glioblastoma: A case report
Translational Neuroscience, 3 (2012), 2; 213-216. https://doi.org/10.2478/s13380-012-0017-x
Čupić, Hrvoje; Sajko, Tomislav; Sesar, Nikolina; Ivica, Mihovil; Pažanin, Leo

Institutional repository: Repository of the Sestre milosrdnice University Hospital Center

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Čupić, H., Sajko, T., Sesar, N., Ivica, M. & Pažanin, L. (2012). Malignant transformation of grade II ganglioglioma to glioblastoma: A case report. Translational Neuroscience, 3. (2), 213-216. doi: 10.2478/s13380-012-0017-x

Čupić, Hrvoje, et al. "Malignant transformation of grade II ganglioglioma to glioblastoma: A case report." Translational Neuroscience, vol. 3, no. 2, 2012, pp. 213-216. https://doi.org/10.2478/s13380-012-0017-x

Čupić, Hrvoje, Tomislav Sajko, Nikolina Sesar, Mihovil Ivica and Leo Pažanin. "Malignant transformation of grade II ganglioglioma to glioblastoma: A case report." Translational Neuroscience 3, no. 2 (2012): 213-216. https://doi.org/10.2478/s13380-012-0017-x

Čupić, H., et al. (2012) 'Malignant transformation of grade II ganglioglioma to glioblastoma: A case report', Translational Neuroscience, 3(2), pp. 213-216. doi: 10.2478/s13380-012-0017-x

Čupić H, Sajko T, Sesar N, Ivica M, Pažanin L. Malignant transformation of grade II ganglioglioma to glioblastoma: A case report. Translational Neuroscience [Internet]. 2012 [cited 2024 December 02];3(2):213-216. doi: 10.2478/s13380-012-0017-x

H. Čupić, T. Sajko, N. Sesar, M. Ivica and L. Pažanin, "Malignant transformation of grade II ganglioglioma to glioblastoma: A case report", Translational Neuroscience, vol. 3, no. 2, pp. 213-216, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:346485. [Accessed: 02 December 2024]

Metadata
Title (english)Malignant transformation of grade II ganglioglioma to glioblastoma: A case report
AuthorHrvoje Čupić
AuthorTomislav Sajko
AuthorNikolina Sesar
AuthorMihovil Ivica
AuthorLeo Pažanin
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Abstract (english)
Gangliogliomas are well differentiated and slowly growing neuroepithelial tumors composed of neoplastic ganglion cells and neoplastic glial cells corresponding mostly to the World Health Organization grade I tumors. However, some of these tumors disclose histologically more malignant glial component and correspond to grade II or grade III tumors. We report a case of left temporal lobe tumor in a 42-year-old woman fulfilling the diagnostic criteria for atypical (grade II) ganglioglioma with high Ki-67 proliferation index and p53 immunoreactive tumor cells. In spite of gross total removal of the tumor, it recurred eight months after surgery. Histopathological examination of the recurrent tumor revealed that it had undergone malignant transformation into a glioblastoma. This case indicates that gangliogliomas with high Ki-67 proliferating index and p53 immunoreactivity should be carefully monitored for recurrence and malignant progression regardless of their morphological grading and seemingly total surgical removal.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleTranslational Neuroscience
Numberingvol. 3, no. 2, pp. 213-216
p-ISSN2081-6936
DOIhttps://doi.org/10.2478/s13380-012-0017-x
URN:NBNurn:nbn:hr:220:346485
Publication2012
Document URLhttps://link.springer.com/article/10.2478/s13380-012-0017-x
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) icon
Created on2024-01-15 10:18:20