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Scientific paper - Case study
Acquired Factor V Inhibitor: A Case Report
Acta clinica Croatica, 45 (2006), 3; 199-201. urn:nbn:hr:220:473739
Gaćina, Petar; Kušec, Rajko; Čaržavec, Dubravka; Raić, Biserka; Stančić, Vladimir

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Gaćina, P., Kušec, R., Čaržavec, D., Raić, B. & Stančić, V. (2006). Acquired Factor V Inhibitor: A Case Report. Acta clinica Croatica, 45. (3), 199-201. Retrieved from https://urn.nsk.hr/urn:nbn:hr:220:473739

Gaćina, Petar, et al. "Acquired Factor V Inhibitor: A Case Report." Acta clinica Croatica, vol. 45, no. 3, 2006, pp. 199-201. https://urn.nsk.hr/urn:nbn:hr:220:473739

Gaćina, Petar, Rajko Kušec, Dubravka Čaržavec, Biserka Raić and Vladimir Stančić. "Acquired Factor V Inhibitor: A Case Report." Acta clinica Croatica 45, no. 3 (2006): 199-201. https://urn.nsk.hr/urn:nbn:hr:220:473739

Gaćina, P., et al. (2006) 'Acquired Factor V Inhibitor: A Case Report', Acta clinica Croatica, 45(3), pp. 199-201. Available at: https://urn.nsk.hr/urn:nbn:hr:220:473739 (Accessed 10 November 2024)

Gaćina P, Kušec R, Čaržavec D, Raić B, Stančić V. Acquired Factor V Inhibitor: A Case Report. Acta clinica Croatica [Internet]. 2006 [cited 2024 November 10];45(3):199-201. Available at: https://urn.nsk.hr/urn:nbn:hr:220:473739

P. Gaćina, R. Kušec, D. Čaržavec, B. Raić and V. Stančić, "Acquired Factor V Inhibitor: A Case Report", Acta clinica Croatica, vol. 45, no. 3, pp. 199-201, 2006. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:473739. [Accessed: 10 November 2024]

Metadata
Title (english)Acquired Factor V Inhibitor: A Case Report
Title (croatian)Stečeni inhibitor faktora V: prikaz slučaja
AuthorPetar Gaćina
AuthorRajko Kušec
AuthorDubravka Čaržavec
AuthorBiserka Raić
AuthorVladimir Stančić
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
A 19-year-old asymptomatic man who was admitted to our hospital for investigation of prolonged screening coagulation assays, prothrombin time and activated partial thromboplastin time is presented. Further evaluation revealed factor V deficiency and the presence of specific factor V inhibitors. The appearance of these inhibitors may be associated with administration of some antibiotics, topical bovine thrombin preparations containing bovine factor V during surgical or dental procedures, after blood transfusions and in patients with malignancy or autoimmune diseases. Factor V inhibitors may also develop spontaneously in patients without any clearly identifiable cause. Our patient had no personal or family history of bleeding tendency or thromboembolic event. There is a general consensus that asymptomatic patients should not be treated regardless of their inhibitor titer and residual factor V levels.
Abstract (croatian)
Prikazan je slučaj 19-godišnjeg bolesnika bez simptoma, koji je upućen u našu bolnicu zbog ispitivanja uzroka produljenih probnih testova zgrušavanja, protrombinskog vremena i aktiviranog parcijalnog tromboplastinskog vremena. Daljnje istraživanje ukazalo je na nedostatak faktora V i prisutnost specifičnog inhibitora faktora V. Prisutnost ovih inhibitora može biti povezana s primjenom antibiotika, goveđeg trombina koji sadrži goveđi faktor V primijenjenih lokalno za vrijeme kirurških i zubnih zahvata, nakon transfuzije krvi i u bolesnika s malignim ili autoimunim bolestima. Inhibitori faktora V mogu također nastati spontano u bolesnika bez jasno otkrivenog uzroka. Naš bolesnik i njegova obitelj nisu imali anamnestičkih podataka o sklonosti krvarenju niti tromboemboliji. Opći je stav da bolesnike bez simptoma nije potrebno liječiti, bez obzira na titar inhibitora i preostalu razinu faktora V.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 45, no. 3, pp. 199-201
p-ISSN0353-9466
e-ISSN1333-9451
URN:NBNurn:nbn:hr:220:473739
Publication2006
Document URLhttps://hrcak.srce.hr/14063
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-08-24 12:32:39