Depression is a psychological disorder that has been increasingly seen lately. It manifests itself through many symptoms, such as mood swings, loss of interest, self-esteem, loss of appetite or sleep, and similar. Symptoms can affect all dimensions of a person, especially the spiritual dimension. It affects the normal course of life. Depression typically finds its roots in a normal reaction to a stressful situation in life. A part of such a normal experience is a feeling of sadness, which is the first sign of a psychological disorder. Depression is often the cause of suicidality. Today there are many psychotherapy approaches and methods of curing depression. The most common ones are psychotherapy, pharmacotherapy, and methods of treating depression. We must not omit the support of family and environment. The most effective medicine is faith which permeates through the spirit of the method and moaning which represents the very essence of the work. It is necessary to give hope and help to the sick people. They see God's tenderness that encourages them to choose life and find meaning. We will open to hagioterapy and logotherapy and at the end to pastoral support sensitive groups of society. The road is paved by faith, hope, and love, and is the only path to meaning that leads to God. He will recover and save.