prikaz prve stranice dokumenta Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes
  Download
PDF 1.65 MB
Scientific paper - Original scientific paper
Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes
Biomedicines, 11 (2023), 8; 2242. https://doi.org/10.3390/biomedicines11082242
Bulum, Tomislav; Tomić, Martina; Vrabec, Romano; Brkljačić, Neva; Ljubić, Spomenka

Institutional repository: Merkur University Hospital Repository

Cite this document

Bulum, T., Tomić, M., Vrabec, R., Brkljačić, N. & Ljubić, S. (2023). Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes. Biomedicines, 11. (8), 2242. doi: 10.3390/biomedicines11082242

Bulum, Tomislav, et al. "Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes." Biomedicines, vol. 11, no. 8, 2023, pp. 2242. https://doi.org/10.3390/biomedicines11082242

Bulum, Tomislav, Martina Tomić, Romano Vrabec, Neva Brkljačić and Spomenka Ljubić. "Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes." Biomedicines 11, no. 8 (2023): 2242. https://doi.org/10.3390/biomedicines11082242

Bulum, T., et al. (2023) 'Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes', Biomedicines, 11(8), pp. 2242. doi: 10.3390/biomedicines11082242

Bulum T, Tomić M, Vrabec R, Brkljačić N, Ljubić S. Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes. Biomedicines [Internet]. 2023 August 10 [cited 2024 November 30];11(8):2242. doi: 10.3390/biomedicines11082242

T. Bulum, M. Tomić, R. Vrabec, N. Brkljačić and S. Ljubić, "Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes", Biomedicines, vol. 11, no. 8, pp. 2242, August 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:264:464094. [Accessed: 30 November 2024]

Metadata
Title (english)Systolic and diastolic blood pressure are independent risk factors for diabetic retinopathy in patients with type 2 diabetes
AuthorTomislav Bulum
AuthorMartina Tomić
AuthorRomano Vrabec
AuthorNeva Brkljačić
AuthorSpomenka Ljubić
Author's institution(Merkur University Hospital)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
Abstract (english)
Background and aims: Diabetic retinopathy (DR) is a microvascular complication of diabetes and represents the leading cause of blindness in working-age adults. The aim of this study was to investigate the risk factors for DR in patients with type 2 diabetes (T2DM) with and without diabetic nephropathy (DN). Methods: A total of 160 patients with T2DM were included in the study. Photodocumented retinopathy status was determined according to the EURODIAB protocol. Renal function was determined using creatinine-based estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR). Binary univariate and multiple logistic regression analyses were performed to determine the main predictors of DR. Results: The prevalence of DR in this studied sample was 46.3%. No significant correlation was observed between DR and age, body mass index, serum lipids, and renal function. Binary logistic regression analysis (no DR/DR) showed that longer diabetes duration (p = 0.008), poor glycemic control (HbA1c) (p = 0.008), higher systolic blood pressure (p = 0.001), and diastolic blood pressure (p = 0.003) were the main predictors of DR in patients with T2DM. However, the influence of systolic blood pressure (AOR = 1.06, p = 0.004) and diastolic blood pressure (AOR = 1.12, p = 0.007) on DR development remained significant even after adjustment for diabetes duration and HbA1c. Conclusions: Our results suggest that systolic and diastolic blood pressure are independent risk factors for DR in patients with T2DM.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiomedicines
Numberingvol. 11, no. 8, p. 2242, 2242
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines11082242
URN:NBNurn:nbn:hr:264:464094
Publication2023-08-10
Document URLhttps://www.mdpi.com/2227-9059/11/8/2242
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-08-21 10:10:48