prikaz prve stranice dokumenta FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19
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Scientific paper - Original scientific paper
FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19
Journal of clinical medicine, 10 (2021), 19; 4355. https://doi.org/10.3390/jcm10194355
Zelenika, Marko; Lucijanić, Marko; Bokun, Tomislav; Božin, Tonći; Barišić Jaman, Mislav; Tješić Drinković, Ida; Paštrović, Frane; Madir, Anita; Lukšić, Ivica; Piskač Živković, Nevenka; Luetić, Krešimir; Krznarić, Željko; Ostojić, Rajko; Filipec Kanižaj, Tajana; Bogadi, Ivan; Virović Jukić, Lucija; Kukla, Michal; Grgurević, Ivica More authors...

Institutional repository: Merkur University Hospital Repository

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Zelenika, M., Lucijanić, M., Bokun, T., Božin, T., Barišić Jaman, M., Tješić Drinković, I. ... Grgurević, I. (2021). FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19. Journal of clinical medicine, 10. (19), 4355. doi: 10.3390/jcm10194355

Zelenika, Marko, et al. "FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19." Journal of clinical medicine, vol. 10, no. 19, 2021, p. 4355. https://doi.org/10.3390/jcm10194355

Zelenika, Marko, Marko Lucijanić, Tomislav Bokun, Tonći Božin, Mislav Barišić Jaman, Ida Tješić Drinković, Frane Paštrović, et al. "FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19." Journal of clinical medicine 10, no. 19 (2021): 4355. https://doi.org/10.3390/jcm10194355

Zelenika, M., et al. (2021) 'FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19', Journal of clinical medicine, 10(19), p. 4355. doi: 10.3390/jcm10194355

Zelenika M, Lucijanić M, Bokun T, Božin T, Barišić Jaman M, Tješić Drinković I, and sur.. FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19. Journal of clinical medicine [Internet]. 2021 September 24 [cited 2024 December 26];10(19):4355. doi: 10.3390/jcm10194355

M. Zelenika, et al., "FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19", Journal of clinical medicine, vol. 10, no. 19, p. 4355, September 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:264:377422. [Accessed: 26 December 2024]

Metadata
Title (english)FibroScan-AST score predicts 30-day mortality or need for mechanical ventilation among patients hospitalized with COVID-19
AuthorMarko Zelenika
AuthorMarko Lucijanić
MBZ: 365834
AuthorTomislav Bokun
AuthorTonći Božin
AuthorMislav Barišić Jaman
AuthorIda Tješić Drinković
AuthorFrane Paštrović
AuthorAnita Madir
AuthorIvica Lukšić
MBZ: 256302
AuthorNevenka Piskač Živković
MBZ: 382495
AuthorKrešimir Luetić
MBZ: 350984
AuthorŽeljko Krznarić
MBZ: 75865
AuthorRajko Ostojić
AuthorTajana Filipec Kanižaj
AuthorIvan Bogadi
AuthorLucija Virović Jukić
MBZ: 317943
AuthorMichal Kukla
AuthorIvica Grgurević
MBZ: 325714
Author's institution(Merkur University Hospital)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Background: Liver involvement in Coronavirus disease 2019 (COVID-19) has been recognised. We aimed to investigate the correlation of non- invasive surrogates of liver steatosis, fibrosis and inflammation using transient elastography (TE) and FibroScan-AST (FAST) score with (a) clinical severity and (b) 30-day composite outcome of mechanical ventilation (MV) or death among patients hospitalized due to COVID-19. Method: Patients with non-critical COVID-19 at admission were included. Liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) were assessed by TE. Clinical severity of COVID-19 was assessed by 4C Mortality Score (4CMS) and need for high-flow nasal cannula (HFNC) oxygen supplementation. Results: 217 patients were included (66.5% males, median age 65 years, 4.6% with history of chronic liver disease). Twenty- four (11.1%) patients met the 30-day composite outcome. Median LSM, CAP and FAST score were 5.2 kPa, 274 dB/m and 0.31, respectively, and neither was associated with clinical severity of COVID-19 at admission. In multivariate analysis FAST > 0.36 (OR 3.19, p = 0.036), 4CMS (OR 1.68, p = 0.002) and HFNC (OR 7.03, p = 0.001) were independent predictors of adverse composite outcome. Conclusion: Whereas LSM and CAP failed to show correlation with COVID-19 severity and outcomes, FAST score was an independent risk factor for 30- day mortality or need for MV.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleJournal of clinical medicine
Numberingvol. 10, no. 19, p. 4355
p-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm10194355
URN:NBNurn:nbn:hr:264:377422
Publication2021-09-24
Document URLhttps://www.mdpi.com/2077-0383/10/19/4355/htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-12-20 09:15:21