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master's thesis
Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina
Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. urn:nbn:hr:182:137278
Janić, Klaudija
Josip Juraj Strossmayer University of Osijek
Department of Chemistry
Department of Analytical, Organic and Applied Chemistry

Institutional repository: Repository of the Department of Chemistry, Osijek

Cite this document

Janić, K. (2021). Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:182:137278

Janić, Klaudija. "Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. https://urn.nsk.hr/urn:nbn:hr:182:137278

Janić, Klaudija. "Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, 2021. https://urn.nsk.hr/urn:nbn:hr:182:137278

Janić, K. (2021). 'Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, accessed 23 November 2024, https://urn.nsk.hr/urn:nbn:hr:182:137278

Janić K. Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of Chemistry; 2021 [cited 2024 November 23] Available at: https://urn.nsk.hr/urn:nbn:hr:182:137278

K. Janić, "Elektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of Chemistry, Osijek, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:182:137278

Metadata
TitleElektro modulacija kompozitnih filmova kitozan-ugljične nanocijevi za kontrolirano otpuštanje inzulina
Title (english)Electro modulation of composite chitosan-carbon nanotube films for controlled release of insulin
AuthorKlaudija Janić
MentorAleksandar Sečenji (mentor)
Committee memberMartina Medvidović-Kosanović (predsjednik povjerenstva)
Committee memberAleksandar Sečenji (član povjerenstva)
Committee memberMirela Samardžić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of Chemistry
(Department of Analytical, Organic and Applied Chemistry)
Osijek
Defense date and country2021-10-26, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Organic Chemistry
Abstract
Dijabetesu tipa 1 uzrok je apsolutni nedostatak lučenja inzulina. Inzulin se trenutno može davati pacijentu jedino parenteralno odnosno injekcijom ili infuzijom u potkožno tkivo. Kao alternativni način dostave inzulina u ovom je radu istražen koncept za kontrolirano otpuštanje inzulina elektromodulacijom kompozitnih filmova kitozan-ugljične nanocijevi. Kompozitni filmovi kitozan-ugljične nanocijevi sa zarobljenim inzulinom naneseni su na screen printed carbon elektrode drop casting metodom, neutralizirane 0,01 mol/L otopinom NaOH. Paralelno je ispitano otpuštanje inzulina difuzijom i elektromodulacijom, a primijenjeni potencijal za elektromodulaciju bio je -0,60 V. Metoda korištena za određivanje količine otpuštenog inzulina bila je voltametrija s linearnom promjenom potencijala (eng. linear sweep voltametry).
Abstract (english)
Type 1 diabetes is caused by an absolute lack of insulin secretion. Insulin can currently be administered to the patient only parenterally i.e., by injection or infusion into the subcutaneous tissue. As an alternative mode of insulin delivery, this master thesis investigates the concept for controlled insulin release by electromodulation of chitosan-carbon nanotube composite films. Composite films of chitosan-carbon nanotubes with loaded insulin were applied to screen-printed carbon electrodes using a drop-casting method and neutralized with NaOH. Insulin release by diffusion and electromodulation were parallelly tested, and the applied potential for electro modulation was -0.60 V. The method used to determine the amount of insulin released was linear sweep voltammetry.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:182:137278
Study programmeTitle: Graduate University Study of Chemistry; research program; specializations in: Research program
Course: Research program
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-08-04 09:11:29