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undergraduate thesis
Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka
završni rad
Split: University of Split, Faculty of Chemistry and Technology, 2016. urn:nbn:hr:167:437837
Krejčir, Kornelija
University of Split
Faculty of Chemistry and Technology
Division of Chemistry

Institutional repository: Repository of the Faculty of chemistry and technology

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Krejčir, K. (2016). Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad (Undergraduate thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:437837

Krejčir, Kornelija. "Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:167:437837

Krejčir, Kornelija. "Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2016. https://urn.nsk.hr/urn:nbn:hr:167:437837

Krejčir, K. (2016). 'Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad', Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, accessed 17 November 2024, https://urn.nsk.hr/urn:nbn:hr:167:437837

Krejčir K. Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad [Undergraduate thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2016 [cited 2024 November 17] Available at: https://urn.nsk.hr/urn:nbn:hr:167:437837

K. Krejčir, "Antiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad", Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, Split, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:167:437837

Metadata
TitleAntiproliferativna aktivnost vodenog ekstrakta biljke Centaurea ragusina L. na dvije stanične linije raka : završni rad
AuthorKornelija Krejčir
MentorMila Radan (mentor)
Committee memberFranko Burčul (predsjednik povjerenstva)
Committee memberMario Nikola Mužek (član povjerenstva)
Committee memberMila Radan (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Chemistry)
Split
Defense date and country2016-09-23, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Rak (lat. cancer) je pojam koji se koristi za veliku skupinu bolesti u kojima se abnormalne stanice dijele bez kontrole te imaju sposobnost prodiranja i invazije u druga tkiva. Nakupine abnormalnih stanica mogu tvoriti benigne ili maligne tumore. Razlika između njih je u agresivnosti rasta te u tome što maligni daju metastaze i šire se u okolinu, prodirući u okolno tkivo, dok benigni tumori ne daju metastaze na druge organe i ne prodiru u okolno zdravo tkivo, već ga potiskuju odnosno rastu ekspanzivno. Fitoterapeutici ili fitofarmaceutici kao aktivne sastojke sadrže biljke, biljne dijelove i njihove pripravke, a podrazumijevaju standardizirane biljne lijekove sa strogo definiranim sadržajem i sastavom terapijski aktivnih tvari, čija je učinkovitost potvrđena farmakološkim i kliničkim istraživanjima, uz naznaku mogućih nuspojava i interakcija s drugim lijekovima. Cilj ovog rada bio je ispitati antiproliferativno djelovanje vodenih ekstrakta endemske vrste Centaurea ragusina L., koja raste na području Dalmacije, na stanice raka dojke (MB-MDA 231) i raka prostate (T24). Vodeni ekstrakt Centaurea ragusina L. pokazao je dobro antiproliferativno djelovanje na stanice raka prostate i raka dojke.
Abstract (english)
Cancer (lat. cancer) is the term used for a large group of diseases in which abnormal cells divide without control and are capable of penetrating and invading other tissues. Clusters of abnormal cells may form benign or malignant tumors. The difference between them is in the growth aggressivness, and that the malignant tumors can spread and metastasize, penetrating into the surrounding tissue, while benign tumors do not give metastases to other organs and do not invade the surrounding healthy tissue, they grow expansively. Phytotherapeutics or phytopharmaceuticals consist of: plants, plant parts and their extracts, and include standardized herbal drugs with strictly defined content and a composition of a therapeutically active substance. Their effectiveness has been confirmed by pharmacological and clinical research, with the indication of possible side effects and drug interactions. The aim of this study was to examine the antiproliferative activity of aqueous extract of several species of Centaurea ragusina L., which can be found in Dalmatia, on breast cancer cells (MDA-MB 231) and prostate cancer (T24). The aqueous extract of Centaurea ragusina L. showed the best anti-proliferative effect on prostate cancer cells and breast cancer cells.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:437837
Study programmeTitle: Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Public noteKljučne riječi doradio knjižničar/ Key words are revised by the librarian
Created on2017-07-06 08:01:59