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master's thesis
METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS
diplomski rad
Split: University of Split, Faculty of Chemistry and Technology, 2023. urn:nbn:hr:167:079716
Živalj, Patricia
University of Split
Faculty of Chemistry and Technology
Division of Chemistry

Institutional repository: Repository of the Faculty of chemistry and technology

Cite this document

Živalj, P. (2023). METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad (Master's thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:079716

Živalj, Patricia. "METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad." Master's thesis, University of Split, Faculty of Chemistry and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:167:079716

Živalj, Patricia. "METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad." Master's thesis, University of Split, Faculty of Chemistry and Technology, 2023. https://urn.nsk.hr/urn:nbn:hr:167:079716

Živalj, P. (2023). 'METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad', Master's thesis, University of Split, Faculty of Chemistry and Technology, accessed 18 December 2024, https://urn.nsk.hr/urn:nbn:hr:167:079716

Živalj P. METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad [Master's thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2023 [cited 2024 December 18] Available at: https://urn.nsk.hr/urn:nbn:hr:167:079716

P. Živalj, "METABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad", Master's thesis, University of Split, Faculty of Chemistry and Technology, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:167:079716

Metadata
TitleMETABOLIČKA ANALIZA URINA: PRONALAŽENJE BIOMARKERA PREEKLAMSIJE KORIŠTENJEM HS-SPME/GC-MS : diplomski rad
Title (english)METABOLIC ANALYSIS OF URINE: DISCOVERING PREECLAMPSIA BIOMARKERS USING HS-SPME/GC-MS : diploma thesis
AuthorPatricia Živalj
MentorMila Radan (mentor)
Committee memberFranko Burčul (predsjednik povjerenstva)
Committee memberMarina Tranfić Bakić (član povjerenstva)
Committee memberMila Radan (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Chemistry)
Split
Defense date and country2023-10-31, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Preeklampsija je bolest koja se javlja kod trudnih žena povezana s abnormalnom placentacijom koja se manifestira prvenstveno povišenim krvnim tlakom, a može se razviti ili tijekom trudnoće ili nakon nje. Može uzrokovati trajno oštećenje tkiva što dovodi do drastičnog opadanja kvalitete života i zdravlja djeteta ili majke, a u konačnici može dovesti i do njihove smrti. Nažalost, ova bolest još je nedovoljno istražena i ponekad se ne stigne primijetiti dovoljno rano da ne ostavi posljedice. Ideja ovog rada je obradom uzoraka urina zdravih trudnica i trudnica koje boluju od preeklampsije koristeći metodu HS-SPME/GC-MS, detektirati prisutne hlapljive organske spojeve. Korištenjem spektara masa i knjižnica spektara masa NIST, cilj je identificirati pojedini metabolit koji bi potencijalno mogao poslužiti kao biomarker za preeklampsiju.
Abstract (english)
Preeclampsia is a disease that occurs in pregnant women and is associated with abnormal placental development. It primarily manifests as high blood pressure and can develop during or after pregnancy. It can cause permanent tissue damage, leading to a decline in the quality of life and health of the child or mother, and ultimately may even lead to their death. Unfortunately, this disease is still insufficiently understood and sometimes goes unnoticed until it is too late to prevent its consequences. The idea of this study is to analyze urine samples from healthy pregnant women and pregnant women with preeclampsia using the HS-SPME/GC-MS method to detect volatile organic compounds. By using mass spectra and NIST-mass libraries, the goal is to identify specific metabolites that could potentially serve as biomarkers for preeclampsia.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:079716
Study programmeTitle: Chemistry; specializations in: Environmental Protection, Organic Chemistry and Biochemistry
Course: Environmental Protection
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-12-01 10:16:14