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undergraduate thesis
Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima
završni rad
Split: University of Split, Faculty of Chemistry and Technology, 2021. urn:nbn:hr:167:542489
Golubić, Glorija
University of Split
Faculty of Chemistry and Technology
Division of Chemistry

Institutional repository: Repository of the Faculty of chemistry and technology

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Golubić, G. (2021). Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad (Undergraduate thesis). Split: University of Split, Faculty of Chemistry and Technology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:167:542489

Golubić, Glorija. "Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:167:542489

Golubić, Glorija. "Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad." Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, 2021. https://urn.nsk.hr/urn:nbn:hr:167:542489

Golubić, G. (2021). 'Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad', Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, accessed 23 November 2024, https://urn.nsk.hr/urn:nbn:hr:167:542489

Golubić G. Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad [Undergraduate thesis]. Split: University of Split, Faculty of Chemistry and Technology; 2021 [cited 2024 November 23] Available at: https://urn.nsk.hr/urn:nbn:hr:167:542489

G. Golubić, "Pregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad", Undergraduate thesis, University of Split, Faculty of Chemistry and Technology, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:167:542489

Metadata
TitlePregled odabranih metoda za određivanje klozapina u farmakološkim pripravcima i biološkim uzorcima : završni rad
Title (english)Review of selected methods for determination of clozapine in pharmacological preparations and biological samples : bachelor thesis
AuthorGlorija Golubić
MentorMaša Buljac (mentor)
Committee memberLea Kukoč Modun (predsjednik povjerenstva)
Committee memberMarijo Buzuk (član povjerenstva)
Committee memberMaša Buljac (član povjerenstva)
GranterUniversity of Split
Faculty of Chemistry and Technology
(Division of Chemistry)
Split
Defense date and country2021-09-27, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Klozapin je lijek koji spada u skupinu atipičnih antipsihotika. Koristi se kao terapija za shizofreniju rezistentnu na liječenje. Kako bi se poboljšao klinički ishod liječenja i smanjila mogućnost nuspojava, u novije vrijeme se primjenjuje terapijsko praćenje koncentracije lijeka u krvi. Iz navedenih razloga, razvoj preciznih i osjetljivih analitičkih metoda za određivanje klozapina u različitim uzorcima popularna je tema brojnih istraživačkih radova. Rad opisuje odabrane kromatografske i voltametrijske metode analize uzoraka te njihovu praktičnu primjenu za određivanje klozapina u farmaceutskim oblicima i različitim biološkim uzorcima. Na temelju pregleda različitih znanstvenih radova, ovaj rad uspoređuje rezultate metoda određivanja klozapina i prikazuje prednosti i nedostatke opisanih metoda.
Abstract (english)
Clozapine is a drug that belongs to the group of atypical antipsychotics. It is used as a therapy for treatment-resistant schizophrenia. In order to improve the clinical outcome of treatment and reduce the possibility of side effects, therapeutic monitoring of drug concentration in the blood has recently been applied. For these reasons, the development of precise and sensitive analytical methods for the determination of clozapine in various samples is a popular topic of numerous research papers. This paper describes selected chromatographic and voltammetric methods of sample analysis and their practical application for the determination of clozapine in pharmaceutical forms and different biological samples. Based on a review of various scientific papers, this paper compares the results of clozapine determination methods and presents the advantages and disadvantages of the described methods.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:167:542489
Study programmeTitle: Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-12-15 11:46:19