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Professional paper - Review paper
Osteoporoza u djece s upalnim bolestima crijeva
Medicina Fluminensis : Medicina Fluminensis, 49 (2013), 1; 4-11. urn:nbn:hr:184:187495
Baraba Dekanić, Kristina; Crnčević-Orlić, Željka; Peršić, Mladen

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Baraba Dekanić, K., Crnčević Orlić, Ž. & Peršić, M. (2013). Osteoporoza u djece s upalnim bolestima crijeva. Medicina Fluminensis : Medicina Fluminensis, 49. (1), 4-11. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:187495

Baraba Dekanić, Kristina, et al. "Osteoporoza u djece s upalnim bolestima crijeva." Medicina Fluminensis : Medicina Fluminensis, vol. 49, no. 1, 2013, pp. 4-11. https://urn.nsk.hr/urn:nbn:hr:184:187495

Baraba Dekanić, Kristina, Željka Crnčević Orlić and Mladen Peršić. "Osteoporoza u djece s upalnim bolestima crijeva." Medicina Fluminensis : Medicina Fluminensis 49, no. 1 (2013): 4-11. https://urn.nsk.hr/urn:nbn:hr:184:187495

Baraba Dekanić, K., Crnčević Orlić, Ž. and Peršić, M. (2013) 'Osteoporoza u djece s upalnim bolestima crijeva', Medicina Fluminensis : Medicina Fluminensis, 49(1), pp. 4-11. Available at: https://urn.nsk.hr/urn:nbn:hr:184:187495 (Accessed 28 April 2024)

Baraba Dekanić K, Crnčević Orlić Ž, Peršić M. Osteoporoza u djece s upalnim bolestima crijeva. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2013 March 04 [cited 2024 April 28];49(1):4-11. Available at: https://urn.nsk.hr/urn:nbn:hr:184:187495

K. Baraba Dekanić, Ž. Crnčević Orlić and M. Peršić, "Osteoporoza u djece s upalnim bolestima crijeva", Medicina Fluminensis : Medicina Fluminensis, vol. 49, no. 1, pp. 4-11, March 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:187495. [Accessed: 28 April 2024]

Metadata
Title (croatian)Osteoporoza u djece s upalnim bolestima crijeva
Title (english)Osteoporosis in children with inflammatory bowel disease
AuthorKristina Baraba Dekanić
AuthorŽeljka Crnčević-Orlić
AuthorMladen Peršić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pediatrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (croatian)
Upalna bolest crijeva obuhvaća Crohnovu bolest, ulcerozni kolitis i nediferencirani kolitis, a u 25 % oboljelih javlja se prije 20. godine života. Osteoporoza je komplikacija upalne bolesti crijeva čija je glavna klinički važna manifestacija povećan rizik za prijelome. U bolesnika dječje i odrasle dobi s upalnom bolešću crijeva učestalost osteopenije i osteoporoze je do 70 %. Gustoću kostiju procjenjujemo kvantitativnom kompjutoriziranom tomografijom, kvantitativnom ultrasonografijom i osteodenzitometrijom. Osteodenzitometrija je zlatni standard u procjeni koštane gustoće. U djece s upalnom bolesti crijeva osnovni uzroci osteoporoze su pothranjenost, kortikosteroidna terapija i povišena razina proupalnih čimbenika. Liječenje osteoporoze u djece temelji se na smanjenju ili eliminaciji faktora rizika na koje se može utjecati. To su adekvatan, za dob odgovarajući unos kalcija i vitamina D, optimalna tjelesna masa, dostatno kretanje, ispravak svakog hormonalnog poremećaja te ublažavanje podliježeće bolesti. Farmakoterapija se koristi onda kada opće mjere liječenja nisu dovele do poboljšanja, a u djece u obzir dolaze samo bisfosfonati. Odluka o farmakoterapiji uvijek je individualna.
Abstract (english)
Inflammatory bowel disease (IBD) consists of Crohn disease, ulcerative colitis and indeterminate colitis and 25 % of patients present before 20 years of age. Osteoporosis is a well known complication of inflammatory bowel disease, the main clinically important manifestation of which is fracture. In children and adults with inflammatory bowel disease the rate of osteopenia and osteoporosis is up to 70 %. Bone mineral density is evaluated by quantitative computed tomography, quantitative ultrasonography and dual-energy X-ray absorptiometry (DEXA). Dual-energy X-ray absorptiometry is the „golden standard” in bone mineral density evaluation. In children with IBD main causes of osteoporosis are malnutrition, corticosteroid therapy and elevated levels of proinflammatory factors. The principles of osteoporosis treatment in children are minimizing or eliminating changeable risk factors. These are adequate calcium and vitamin D uptake according to the patient’s age, optimal body mass, adequate exercise, and correction of hormonal imbalance and treatment of underlying disease. Pharmacotherapy is used only when general measures were not successful, and only bisphosphonates can be used in children. The approach to the pharmacotherapy is always individual.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 49, no. 1, pp. 4-11
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:187495
Publication2013-03-04
Document URLhttp://hrcak.srce.hr/98603
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-05-12 07:58:05