prikaz prve stranice dokumenta Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers
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Scientific paper - Original scientific paper
Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers
Collegium antropologicum, 33 (2009), 4; 1323-1328. urn:nbn:hr:184:297194
Jeran, Nina; Havaš Auguštin, Dubravka; Grahovac, Blaženka; Kapović, Miljenko; Metspalu, Ene; Villems, Richard; Rudan, Pavao

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Jeran, N., Havaš Auguštin, D., Grahovac, B., Kapović, M., Metspalu, E., Villems, R. & Rudan, P. (2009). Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers. Collegium antropologicum, 33. (4), 1323-1328. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:297194

Jeran, Nina, et al. "Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers." Collegium antropologicum, vol. 33, no. 4, 2009, pp. 1323-1328. https://urn.nsk.hr/urn:nbn:hr:184:297194

Jeran, Nina, Dubravka Havaš Auguštin, Blaženka Grahovac, Miljenko Kapović, Ene Metspalu, Richard Villems and Pavao Rudan. "Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers." Collegium antropologicum 33, no. 4 (2009): 1323-1328. https://urn.nsk.hr/urn:nbn:hr:184:297194

Jeran, N., et al. (2009) 'Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers', Collegium antropologicum, 33(4), pp. 1323-1328. Available at: https://urn.nsk.hr/urn:nbn:hr:184:297194 (Accessed 09 November 2024)

Jeran N, Havaš Auguštin D, Grahovac B, Kapović M, Metspalu E, Villems R, and sur.. Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers. Collegium antropologicum [Internet]. 2009 December 01 [cited 2024 November 09];33(4):1323-1328. Available at: https://urn.nsk.hr/urn:nbn:hr:184:297194

N. Jeran, et al., "Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers", Collegium antropologicum, vol. 33, no. 4, pp. 1323-1328, December 2009. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:297194. [Accessed: 09 November 2024]

Metadata
Title (english)Mitochondrial DNA Heritage of Cres Islanders – Example of Croatian Genetic Outliers
AuthorNina Jeran
AuthorDubravka Havaš Auguštin
AuthorBlaženka Grahovac
AuthorMiljenko Kapović
AuthorEne Metspalu
AuthorRichard Villems
AuthorPavao Rudan
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
Diversity of mitochondrial DNA (mtDNA) lineages of the Island of Cres was determined by high-resolution phylogenetic analysis on a sample of 119 adult unrelated individuals from eight settlements. The composition of mtDNA pool of this Island population is in contrast with other Croatian and European populations. The analysis revealed the highest frequency of haplogroup U (29.4%) with the predominance of one single lineage of subhaplogroup U2e (20.2%). Haplogroup H is the second most prevalent one with only 27.7%. Other very interesting features of contemporary Island population are extremely low frequency of haplogroup J (only 0.84%), and much higher frequency of haplogroup W (12.6%) comparing to other Croatian and European populations. Especially interesting finding is a strikingly higher frequency of haplogroup N1a (9.24%) presented with African/south Asian branch almost absent in Europeans, while its European sister-branch, proved to be highly prevalent among Neolithic farmers, is present in contemporary Europeans with only 0.2%. Haplotype analysis revealed that only five mtDNA lineages account for almost 50% of maternal genetic heritage of this island and they present supposed founder lineages. All presented findings confirm that genetic drift, especially founder effect, has played significant role in shaping genetic composition of the isolated population of the Island of Cres. Due to presented data contemporary population of Cres Island can be considered as genetic »outlier« among Croatian populations.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 33, no. 4, pp. 1323-1328
p-ISSN0350-6134
URN:NBNurn:nbn:hr:184:297194
Publication2009-12-01
Document URLhttp://hrcak.srce.hr/51521
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-08-01 08:49:49