prikaz prve stranice dokumenta Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review
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Scientific paper - Original scientific paper
Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review
Fertility and Sterility, 99 (2013), 6; 1663-1667. https://doi.org/10.1016/j.fertnstert.2013.01.101
Pereza, Nina; Črnjar, Ksenija; Buretić-Tomljanović, Alena; Volk, Marija; Kapović, Miljenko; Peterlin, Borut; Ostojić, Saša

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Pereza, N., Črnjar, K., Buretić Tomljanović, A., Volk, M., Kapović, M., Peterlin, B. & Ostojić, S. (2013). Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review. Fertility and Sterility, 99. (6), 1663-1667. doi: 10.1016/j.fertnstert.2013.01.101

Pereza, Nina, et al. "Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review." Fertility and Sterility, vol. 99, no. 6, 2013, pp. 1663-1667. https://doi.org/10.1016/j.fertnstert.2013.01.101

Pereza, Nina, Ksenija Črnjar, Alena Buretić Tomljanović, Marija Volk, Miljenko Kapović, Borut Peterlin and Saša Ostojić. "Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review." Fertility and Sterility 99, no. 6 (2013): 1663-1667. https://doi.org/10.1016/j.fertnstert.2013.01.101

Pereza, N., et al. (2013) 'Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review', Fertility and Sterility, 99(6), pp. 1663-1667. doi: 10.1016/j.fertnstert.2013.01.101

Pereza N, Črnjar K, Buretić Tomljanović A, Volk M, Kapović M, Peterlin B, and sur.. Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review. Fertility and Sterility [Internet]. 2013 [cited 2024 May 02];99(6):1663-1667. doi: 10.1016/j.fertnstert.2013.01.101

N. Pereza, et al., "Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review", Fertility and Sterility, vol. 99, no. 6, pp. 1663-1667, 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:262926. [Accessed: 02 May 2024]

Metadata
Title (english)Y chromosome azoospermia factor region microdeletions are not associated with idiopathic recurrent spontaneous abortion in a Slovenian population: association study and literature review
AuthorNina Pereza
AuthorKsenija Črnjar
AuthorAlena Buretić-Tomljanović
AuthorMarija Volk
AuthorMiljenko Kapović
AuthorBorut Peterlin
AuthorSaša Ostojić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
Objective To investigate the potential association of Y chromosome microdeletions with idiopathic recurrent spontaneous abortion (IRSA) in a Slovenian population and compare our results with those of previously published studies in different populations, with the intention of clarifying the potential impact of Y chromosome microdeletions on IRSA. Design Case–control and association study. Setting Departments of gynecology and obstetrics and university-based research laboratory. Patient(s) Male partners of 148 couples with at least three spontaneous pregnancy losses of unknown etiology, and 148 fertile men. Intervention(s) Multiplex polymerase chain reactions. Main Outcome Measure(s) Azoospermia factor (AZF) regions were tested for Y chromosome microdeletions according to European Academy of Andrology/European Molecular Genetics Quality Network guidelines. The PubMed database was searched to retrieve articles linking Y chromosome microdeletions and susceptibility to IRSA. Result(s) None of the IRSA or control men had microdeletions in the AZFa, AZFb, or AZFc regions. A total of nine previous studies examined the relationship between Y chromosome microdeletions and IRSA, yielding contradictory results, which we discuss in detail. Conclusion(s) On the basis of our comparisons, it is unlikely that Y chromosome microdeletions contribute to IRSA and are therefore currently not recommended for the routine evaluation of IRSA couples.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleFertility and Sterility
Numberingvol. 99, no. 6, pp. 1663-1667
p-ISSN0015-0282
DOIhttps://doi.org/10.1016/j.fertnstert.2013.01.101
URN:NBNurn:nbn:hr:184:262926
Publication2013
Document URLhttp://dx.doi.org/10.1016/j.fertnstert.2013.01.101 showArticle Info
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2017-08-02 09:21:59