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Scientific paper - Preliminary note / Short communication
Systemic Character of Legionnaires’ Disease – A Murine Model
Food Technology and Biotechnology, 41 (2003), 3; 227-230. urn:nbn:hr:184:753620
Šantić, Marina; Bozic, Michael; Kessler, Harald H.; Dorić, Miljenko

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Šantić, M., Bozic, M., Kessler, H. H. & Dorić, M. (2003). Systemic Character of Legionnaires’ Disease – A Murine Model. Food Technology and Biotechnology, 41. (3), 227-230. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:753620

Šantić, Marina, et al. "Systemic Character of Legionnaires’ Disease – A Murine Model." Food Technology and Biotechnology, vol. 41, no. 3, 2003, pp. 227-230. https://urn.nsk.hr/urn:nbn:hr:184:753620

Šantić, Marina, Michael Bozic, Harald H. Kessler and Miljenko Dorić. "Systemic Character of Legionnaires’ Disease – A Murine Model." Food Technology and Biotechnology 41, no. 3 (2003): 227-230. https://urn.nsk.hr/urn:nbn:hr:184:753620

Šantić, M., et al. (2003) 'Systemic Character of Legionnaires’ Disease – A Murine Model', Food Technology and Biotechnology, 41(3), pp. 227-230. Available at: https://urn.nsk.hr/urn:nbn:hr:184:753620 (Accessed 10 May 2024)

Šantić M, Bozic M, Kessler HH, Dorić M. Systemic Character of Legionnaires’ Disease – A Murine Model. Food Technology and Biotechnology [Internet]. 2003 September 15 [cited 2024 May 10];41(3):227-230. Available at: https://urn.nsk.hr/urn:nbn:hr:184:753620

M. Šantić, M. Bozic, H. H. Kessler and M. Dorić, "Systemic Character of Legionnaires’ Disease – A Murine Model", Food Technology and Biotechnology, vol. 41, no. 3, pp. 227-230, September 2003. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:753620. [Accessed: 10 May 2024]

Metadata
Title (english)Systemic Character of Legionnaires’ Disease – A Murine Model
AuthorMarina Šantić
AuthorMichael Bozic
AuthorHarald H. Kessler
AuthorMiljenko Dorić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
In contrast to lung infection caused by Legionella pneumophila, little is known about the pathogenesis of this disease in other organs. In this study, we analyzed the number of colony forming units (CFU) of legionellae not only in lungs but also in EDTA plasma, liver, spleen and kidneys. The number of CFU was determined 2, 24, 48, 72 and 168 h after intratracheal inoculation. Results showed that the inflammatory response was mostly pronounced in lungs. Legionellae, however, were also found in EDTA plasma and all the other investigated organs. The duration of infection was most protracted in lungs, with persistence for at least 168 h. In the remaining organs, legionellae were found for a maximum of 72 h after inoculation. Besides the culture methods used for detection of CFU we also used LightCycler (LC) PCR to confirm the presence of bacteria in the blood of intratracheally infected mice. By this method the bacterial DNA could be detected during the first two days of post infection.
Keywords (english)
Languageenglish
Publication typeScientific paper - Preliminary note / Short communication
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleFood Technology and Biotechnology
Numberingvol. 41, no. 3, pp. 227-230
p-ISSN1330-9862
e-ISSN1334-2606
URN:NBNurn:nbn:hr:184:753620
Publication2003-09-15
Document URLhttp://hrcak.srce.hr/118620
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-08-08 06:54:04