prikaz prve stranice dokumenta Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma
  Download
PDF 187.11 KB
Scientific paper - Original scientific paper
Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma
Acta Dermatovenerologica Croatica, 25 (2017), 2; 99-106. urn:nbn:hr:184:774164
Jonjić, Nives; Rajković Molek, Koraljka; Seili-Bekafigo, Irena; Grbac-Ivanković, Svjetlana; Girotto, Neva; Jurišić, Davor; Zamolo, Gordana; Pavlović-Ružić, Ira; Prpić-Massari, Larisa

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

Cite this document

Jonjić, N., Rajković Molek, K., Seili Bekafigo, I., Grbac Ivanković, S., Girotto, N., Jurišić, D. ... Prpić Massari, L. (2017). Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma. Acta Dermatovenerologica Croatica, 25. (2), 99-106. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:774164

Jonjić, Nives, et al. "Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma." Acta Dermatovenerologica Croatica, vol. 25, no. 2, 2017, pp. 99-106. https://urn.nsk.hr/urn:nbn:hr:184:774164

Jonjić, Nives, Koraljka Rajković Molek, Irena Seili Bekafigo, Svjetlana Grbac Ivanković, Neva Girotto, Davor Jurišić, Gordana Zamolo, Ira Pavlović Ružić and Larisa Prpić Massari. "Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma." Acta Dermatovenerologica Croatica 25, no. 2 (2017): 99-106. https://urn.nsk.hr/urn:nbn:hr:184:774164

Jonjić, N., et al. (2017) 'Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma', Acta Dermatovenerologica Croatica, 25(2), pp. 99-106. Available at: https://urn.nsk.hr/urn:nbn:hr:184:774164 (Accessed 23 April 2024)

Jonjić N, Rajković Molek K, Seili Bekafigo I, Grbac Ivanković S, Girotto N, Jurišić D, and sur.. Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma. Acta Dermatovenerologica Croatica [Internet]. 2017 July 20 [cited 2024 April 23];25(2):99-106. Available at: https://urn.nsk.hr/urn:nbn:hr:184:774164

N. Jonjić, et al., "Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma", Acta Dermatovenerologica Croatica, vol. 25, no. 2, pp. 99-106, July 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:774164. [Accessed: 23 April 2024]

Metadata
Title (english)Predictive value of intraoperative sentinel lymph node imprint cytology analysis for metastasis in patients with melanoma
AuthorNives Jonjić
AuthorKoraljka Rajković Molek
AuthorIrena Seili-Bekafigo
AuthorSvjetlana Grbac-Ivanković
AuthorNeva Girotto
AuthorDavor Jurišić
AuthorGordana Zamolo
AuthorIra Pavlović-Ružić
AuthorLarisa Prpić-Massari
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Dermatovenerology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Abstract (english)
<p>Since there are no standardized protocols regarding the detection of microscopic melanoma deposits in sentinel lymph nodes (SLN), the aim of this study was to present our experience with intraoperative cytological evaluation of SLN in patients with melanoma. The study included 475 SLN biopsies (SLNB) from 201 patients with primary cutaneous melanoma of intermediate thickness. Each lymph node was cut in half; touch imprint cytology (TIC) preparations of all cut surfaces were performed and stained according to a modified May-Grünwald-Giemsa method. The results were compared to definitive postoperative histology. Twenty of 25 SLNB positive on TIC proved to be metastatic when compared to definitive histology. Most of 32 SLN that were suspicious but not diagnostic on TIC were proven negative (23/32, 71.8%), while 7 nodes had metastases (one micrometastasis and one with isolated tumor cells only). The majority (94%) of SLNBs negative on TIC remained negative on final histology, while 6% or 25 nodes were positive, mostly with micrometastases or isolated tumor cells (17/25). In frozen sections performed in cases of suspicious or positive SLN cytology, metastasis was confirmed in 80% of positive and in 21.9% of suspicious TIC. Altogether, 49% (27/55) of positive SLNB were identified intraoperatively in 57% (24/42) of patients, and in those cases a complete regional lymph node dissection was performed in the first step. TIC assessment of SLNB with 99% specificity and 57% sensitivity for intraoperative identification of metastasis is useful and beneficial for avoiding a second operative procedure. </p><p> </p>
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleActa Dermatovenerologica Croatica
Numberingvol. 25, no. 2, pp. 99-106
p-ISSN1330-027X
e-ISSN1847-6538
URN:NBNurn:nbn:hr:184:774164
Publication2017-07-20
Document URLhttp://hrcak.srce.hr/185015
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-10-01 17:07:08