prikaz prve stranice dokumenta Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome
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Scientific paper - Original scientific paper
Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome
Croatian medical journal, 53 (2012), 3; 234-238. https://doi.org/10.3325/cmj.2012.53.234
Štimac, Tea; Petrović, Oleg; Krajina, Robert; Prodan, Mirko; Bilić-Zulle, Lidija

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Štimac, T., Petrović, O., Krajina, R., Prodan, M. & Bilić Zulle, L. (2012). Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome. Croatian medical journal, 53. (3), 234-238. doi: 10.3325/cmj.2012.53.234

Štimac, Tea, et al. "Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome." Croatian medical journal, vol. 53, no. 3, 2012, pp. 234-238. https://doi.org/10.3325/cmj.2012.53.234

Štimac, Tea, Oleg Petrović, Robert Krajina, Mirko Prodan and Lidija Bilić Zulle. "Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome." Croatian medical journal 53, no. 3 (2012): 234-238. https://doi.org/10.3325/cmj.2012.53.234

Štimac, T., et al. (2012) 'Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome', Croatian medical journal, 53(3), pp. 234-238. doi: 10.3325/cmj.2012.53.234

Štimac T, Petrović O, Krajina R, Prodan M, Bilić Zulle L. Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome. Croatian medical journal [Internet]. 2012 [cited 2024 November 27];53(3):234-238. doi: 10.3325/cmj.2012.53.234

T. Štimac, O. Petrović, R. Krajina, M. Prodan and L. Bilić Zulle, "Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome", Croatian medical journal, vol. 53, no. 3, pp. 234-238, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:597458. [Accessed: 27 November 2024]

Metadata
Title (english)Lamellar body count as a diagnostic test in predicting neonatal respiratory distress syndrome
AuthorTea Štimac
AuthorOleg Petrović
AuthorRobert Krajina
AuthorMirko Prodan
AuthorLidija Bilić-Zulle
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Gynaecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
Aim :To determine the lamellar body count (LBC) cutoff value for fetal lung maturity and to evaluate the clinical usefulness of LBC in predicting the severity of neonatal respiratory distress syndrome (RDS). Methods A prospective study was conducted from 2002 until 2010. LBC was estimated in uncentrifugated amniotic fluid samples using Cell-Dyn 1800 analyzer. Amniotic fluid samples were obtained by amniocentesis or by puncturing embryonic membranes during cesarean section. The presence of mild, moderate, and severe RDS was assessed by neonatologist. Results A total of 313 patients with singleton pregnancies (24-41 weeks) were included in the study and 294 met the inclusion criteria. RDS was diagnosed in 28 neonates – mild in 8, moderate in 10, and severe in 10. In premature neonates (<37 gestational weeks), significant differences in LBC were only found between the subgroup without RDS and the group with moderate and the group with severe RDS (P < 0.001). In all neonates, significant differences were found between neonates without RDS and neonates with RDS. Using LBC cutoff value of ≥20, 000/µL, sensitivity, specificity, and positive and negative predictive values of LBC in determining mature fetal lungs were 96%, 88%, 45.6%, and 99.5%, respectively. Conclusion This study suggests that LBC cutoff value of ≥20, 000/µL can predict pulmonary maturity and reduce the risk of neonatal respiratory distress syndrome.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian medical journal
Numberingvol. 53, no. 3, pp. 234-238
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2012.53.234
URN:NBNurn:nbn:hr:184:597458
Publication2012
Document URLhttp://bib.irb.hr/811806
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2018-07-24 10:28:02