prikaz prve stranice dokumenta Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection
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Scientific paper - review paper
Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection
Medical microbiology and immunology, 201 (2012), 4; 487-495. https://doi.org/10.1007/s00430-012-0263-0
Mitrović, Maja; Arapović, Jurica; Traven, Luka; Krmpotić, Astrid; Jonjić, Stipan

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Mitrović, M., Arapović, J., Traven, L., Krmpotić, A. & Jonjić, S. (2012). Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection. Medical microbiology and immunology, 201. (4), 487-495. doi: 10.1007/s00430-012-0263-0

Mitrović, Maja, et al. "Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection." Medical microbiology and immunology, vol. 201, no. 4, 2012, pp. 487-495. https://doi.org/10.1007/s00430-012-0263-0

Mitrović, Maja, Jurica Arapović, Luka Traven, Astrid Krmpotić and Stipan Jonjić. "Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection." Medical microbiology and immunology 201, no. 4 (2012): 487-495. https://doi.org/10.1007/s00430-012-0263-0

Mitrović, M., et al. (2012) 'Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection', Medical microbiology and immunology, 201(4), pp. 487-495. doi: 10.1007/s00430-012-0263-0

Mitrović M, Arapović J, Traven L, Krmpotić A, Jonjić S. Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection. Medical microbiology and immunology [Internet]. 2012 [cited 2024 November 23];201(4):487-495. doi: 10.1007/s00430-012-0263-0

M. Mitrović, J. Arapović, L. Traven, A. Krmpotić and S. Jonjić, "Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection", Medical microbiology and immunology, vol. 201, no. 4, pp. 487-495, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:059858. [Accessed: 23 November 2024]

Metadata
Title (english)Innate immunity regulates adaptive immune response: lessons learned from studying the interplay between NK and CD8+ T cells during MCMV infection
AuthorMaja Mitrović
AuthorJurica Arapović
AuthorLuka Traven
AuthorAstrid Krmpotić
AuthorStipan Jonjić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Histology and Embryology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Natural killer (NK) cells play a crucial role in early immune response against cytomegalovirus infection. A large and mounting body of data indicate that these cells are involved in the regulation of the adaptive immune response as well. By using mouse cytomegalovirus (MCMV) as a model, several groups provided novel insights into the role of NK cells in the development and kinetics of antiviral CD8+ T cell response. Depending on infection conditions, virus strain and the genetic background of mice used, NK cells are either positive or negative regulators of the CD8+ T cell response. At present, there is no unique explanation for the observed differences between various experimental systems used. In this review we discuss the mechanisms involved in the interplay between NK and CD8+ T cells in the early control of MCMV infection.
Keywords (english)
Languageenglish
Publication typeScientific paper - review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedical microbiology and immunology
Numberingvol. 201, no. 4, pp. 487-495
p-ISSN0300-8584
DOIhttps://doi.org/10.1007/s00430-012-0263-0
URN:NBNurn:nbn:hr:184:059858
Publication2012
ProjectNumber: 062-0621261-1263
Title (croatian): Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru
Leader: Stipan Jonjić
Jurisdiction: Croatia
Funding stream: ZP
ProjectNumber: 062-0621261-1268
Title (croatian): Uloga imunosubverzivnih citomegalovirusnih gena u latenciji
Leader: Astrid Krmpotić
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://bib.irb.hr/605399
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2018-10-11 11:58:23