prikaz prve stranice dokumenta Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice
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Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice
European Journal of Immunology, 40 (2010), 5; 1241-1243. https://doi.org/10.1002/eji.201040506
Jonjić, Stipan

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Jonjić, S. (2010). Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice. European Journal of Immunology, 40. (5), 1241-1243. doi: 10.1002/eji.201040506

Jonjić, Stipan. "Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice." European Journal of Immunology, vol. 40, no. 5, 2010, pp. 1241-1243. https://doi.org/10.1002/eji.201040506

Jonjić, Stipan. "Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice." European Journal of Immunology 40, no. 5 (2010): 1241-1243. https://doi.org/10.1002/eji.201040506

Jonjić, S. (2010) 'Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice', European Journal of Immunology, 40(5), pp. 1241-1243. doi: 10.1002/eji.201040506

Jonjić S. Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice. European Journal of Immunology [Internet]. 2010 April 06 [cited 2024 May 14];40(5):1241-1243. doi: 10.1002/eji.201040506

S. Jonjić, "Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice", European Journal of Immunology, vol. 40, no. 5, pp. 1241-1243, April 2010. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:345904. [Accessed: 14 May 2024]

Metadata
Title (english)Functional plasticity and robustness are essential characteristics of biological systems: Lessons learned from KLRG1-deficient mice
AuthorStipan Jonjić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Histology and Embryology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Killer cell lectin-like receptor G1 (KLRG1) receptor is considered to be a marker of terminally differentiated NK and T cells and is strongly induced by viral and other infections. KLRG1 is a C-type lectin-like inhibitory receptor, which interacts with members of the cadherin family of molecules leading to the inhibition of T- and NK-cell function. A study in this issue of the European Journal of Immunology addresses the role of KLRG1 in the maturation and differentiation of NK and T cells in vivo. Using KLRG1-deficient mice generated by homologous recombination, the study reveals that KLRG1 is dispensable for NK- and CD8+ T-cell differentiation and function in vivo. This interesting finding is discussed in this Commentary in light of the plasticity and robustness of immune response mechanisms.
Keywords (english)
Languageenglish
Publication typeScientific paper - Other
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleEuropean Journal of Immunology
Numberingvol. 40, no. 5, pp. 1241-1243
p-ISSN0014-2980
DOIhttps://doi.org/10.1002/eji.201040506
URN:NBNurn:nbn:hr:184:345904
Publication2010-04-06
ProjectNumber: 062-0621261-1263
Title (croatian): Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru
Leader: Stipan Jonjić
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://doi.wiley.com/10.1002/eji.201040506
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2018-11-08 22:53:35