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Scientific paper - Case study
Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja
Medicina Fluminensis, 54 (2018), 4; 429-432. https://doi.org/10.21860/medflum2018_207363
Marinelli, Frano; Markić, Dean; Štifter, Sanja; Kukuljan, Melita; Miletić, Damir

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Marinelli, F., Markić, D., Štifter, S., Kukuljan, M. & Miletić, D. (2018). Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja. Medicina Fluminensis, 54. (4), 429-432. doi: 10.21860/medflum2018_207363

Marinelli, Frano, et al. "Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja." Medicina Fluminensis, vol. 54, no. 4, 2018, pp. 429-432. https://doi.org/10.21860/medflum2018_207363

Marinelli, Frano, Dean Markić, Sanja Štifter, Melita Kukuljan and Damir Miletić. "Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja." Medicina Fluminensis 54, no. 4 (2018): 429-432. https://doi.org/10.21860/medflum2018_207363

Marinelli, F., et al. (2018) 'Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja', Medicina Fluminensis, 54(4), pp. 429-432. doi: 10.21860/medflum2018_207363

Marinelli F, Markić D, Štifter S, Kukuljan M, Miletić D. Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja. Medicina Fluminensis [Internet]. 2018 December 01 [cited 2024 April 16];54(4):429-432. doi: 10.21860/medflum2018_207363

F. Marinelli, D. Markić, S. Štifter, M. Kukuljan and D. Miletić, "Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja", Medicina Fluminensis, vol. 54, no. 4, pp. 429-432, December 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:468545. [Accessed: 16 April 2024]

Metadata
Title (croatian)Wünderlich sindrom kao prva manifestacija karcinoma bubrega – prikaz slučaja
Title (english)Wünderlich syndrome as a first manifestation of renal cell carcinoma – case report
AuthorFrano Marinelli
AuthorDean Markić
AuthorSanja Štifter
AuthorMelita Kukuljan
AuthorDamir Miletić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Radiology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Urology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Abstract (croatian)
Cilj: Prikazati spontano, netraumatsko perirenalno krvarenje (Wünderlich sindrom) kao prvu manifestaciju karcinoma bubrega te dijagnostički i terapijski postupak kod takvog bolesnika. Prikaz slučaja: Bolesnica stara 37 godina je došla na hitni medicinski trakt s intenzivnim, naglo nastalim bolovima u lijevom lumbalnom predjelu abdomena; uredno mokri, negira traumu i nema makrohematuriju. Zbog općeg lošeg stanja bolesnica je poslana na hitnu višeslojnu kompjuteriziranu tomografiju (Multi-slice computed tomography, MSCT) abdomena i zdjelice na kojoj je utvrđena inhomogena formacija u gornjem polu lijevog bubrega uz zaključak radiologa da se radi o perirenalnom krvarenju, najvjerojatnije uzrokovanog angiomiolipomom. Urolog se odlučio za hitni operacijski zahvat koji uključuje djelomičnu nefrektomiju lijevog bubrega te evakuaciju hematoma. Patohistološki pregled uputio je na karcinom bubrega kromofobnog tipa koji je uzrokovao krvarenje. Bolesnica se redovito kontrolira, nema znakova recidiva. Zaključak: Wünderlich sindrom je rijetka, potencijalno životno ugrožavajuća manifestacija karcinoma bubrega koja zahtijeva hitni operacijski zahvat. MSCT abdomena i zdjelice je radiološka metoda izbora za akutnu abdominalnu/lumbalnu bol u hemodinamski nestabilnog bolesnika.
Abstract (english)
Aim: To present a case with spontaneous, non-traumatic, perirenal haemorrhage (Wünderlich syndrome) as a first manifestation of renal cell carcinoma. Case report: A 37-year-old female was admitted to the emergency unit with sudden and severe pain in the left lumbar area of abdomen. She has normal voiding, without macrohaematuria or trauma in her medical history. Because of her generally instable state she was referred to emergency multi-slice computed tomography (MSCT) exam of the abdomen and pelvis which reveals inhomogeneous mass in the upper pole of the left kidney. Radiology report indicated perirenal haemorrhage most likely caused by an angiomyolipoma. The patient was operated on by urologist who performed a partial nephrectomy of the left kidney and evacuation of haematoma. Samples were taken for histopathology and cromophobe renal cell carcinoma which caused the perirenal haemorrhage was diagnosed. Our patient is controlled on regular basis, without signs of tumour recurrence. Conclusion: Wünderlich syndrome as the first manifestation of renal cell carcinoma is a very rare but life-threatening manifestation of renal cancer that warrants urgent surgery. MSCT of the abdomen and pelvis is a method of choice in haemodynamically unstable patients with acute abdominal/lumbar pain.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleMedicina Fluminensis
Numberingvol. 54, no. 4, pp. 429-432
p-ISSN1847-6864
e-ISSN1848-1868
DOIhttps://doi.org/10.21860/medflum2018_207363
URN:NBNurn:nbn:hr:184:468545
Publication2018-12-01
Document URLhttps://hrcak.srce.hr/207363
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2018-12-03 16:17:09