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Scientific paper - Original scientific paper
The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx
BioMed Research International, 2019 (2019); 1-6. https://doi.org/10.1155/2019/8142572
Vukelić, Jelena; Dobrila-Dintinjana, Renata; Dekanić, Andrea; Marijić, Blažen; Čubranić, Aleksandar; Braut, Tamara

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Vukelić, J., Dobrila Dintinjana, R., Dekanić, A., Marijić, B., Čubranić, A. & Braut, T. (2019). The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx. BioMed Research International, 2019., 1-6. doi: 10.1155/2019/8142572

Vukelić, Jelena, et al. "The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx." BioMed Research International, vol. 2019, 2019, pp. 1-6. https://doi.org/10.1155/2019/8142572

Vukelić, Jelena, Renata Dobrila Dintinjana, Andrea Dekanić, Blažen Marijić, Aleksandar Čubranić and Tamara Braut. "The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx." BioMed Research International 2019 (2019): 1-6. https://doi.org/10.1155/2019/8142572

Vukelić, J., et al. (2019) 'The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx', BioMed Research International, 2019, pp. 1-6. doi: 10.1155/2019/8142572

Vukelić J, Dobrila Dintinjana R, Dekanić A, Marijić B, Čubranić A, Braut T. The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx. BioMed Research International [Internet]. 2019 January 15 [cited 2024 December 27];2019:1-6. doi: 10.1155/2019/8142572

J. Vukelić, R. Dobrila Dintinjana, A. Dekanić, B. Marijić, A. Čubranić and T. Braut, "The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx", BioMed Research International, vol. 2019, pp. 1-6, January 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:895972. [Accessed: 27 December 2024]

Metadata
Title (english)The Relevance of Assessing the Cell Proliferation Factor Ki-67 in Squamous Cell Carcinoma of the Larynx
AuthorJelena Vukelić
AuthorRenata Dobrila-Dintinjana
AuthorAndrea Dekanić
AuthorBlažen Marijić
AuthorAleksandar Čubranić
AuthorTamara Braut
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Oncology and Radiotherapy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Otorhinolaryngology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Otorhinolaryngology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract (english)
The aim of study was to investigate the expression of the proliferation factor Ki-67 and its relationship with histological grade, cancer stage, and treatment outcome in squamous cell carcinoma of the larynx. Samples from 78 patients with laryngeal cancer were analysed retrospectively. Paraffin sections of tumors were immunohistochemically stained for Ki-67 expression. The patients were divided in two groups according to the proliferative factor values (a low Ki-67 index group - Ki-67≤34 and high Ki-67 index group-Ki-67 >34). Statistical analysis of the data shows significant correlation among histological tumor grade and the value of the Ki-67 proliferative index. There was no correlation between tumoral Ki-67 expression and diagnosis, stage of the disease, or treatment outcome. In conclusion, Ki-67 expression in laryngeal cancer is not the most reliable marker for making precise diagnosis and predicting the clinical course.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBioMed Research International
Numberingvol. 2019, pp. 1-6
p-ISSN2314-6133
e-ISSN2314-6141
DOIhttps://doi.org/10.1155/2019/8142572
URN:NBNurn:nbn:hr:184:895972
Publication2019-01-15
Document URLhttps://www.hindawi.com/journals/bmri/2019/8142572/
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2019-02-20 08:20:01