prikaz prve stranice dokumenta Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients
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Scientific paper - Original scientific paper
Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients
European Neurology, 57 (2007), 4; 203-207. urn:nbn:hr:184:786338
Ristić, Smiljana; Lovrečić, Luca; Starčević-Čizmarević, Nada; Brajenović-Milić, Bojana; Šega Jazbec, Saša; Sepčić, Juraj; Kapović, Miljenko; Peterlin, Borut

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Ristić, S., Lovrečić, L., Starčević Čizmarević, N., Brajenović Milić, B., Šega Jazbec, S., Sepčić, J. ... Peterlin, B. (2007). Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients. European Neurology, 57. (4), 203-207. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:786338

Ristić, Smiljana, et al. "Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients." European Neurology, vol. 57, no. 4, 2007, pp. 203-207. https://urn.nsk.hr/urn:nbn:hr:184:786338

Ristić, Smiljana, Luca Lovrečić, Nada Starčević Čizmarević, Bojana Brajenović Milić, Saša Šega Jazbec, Juraj Sepčić, Miljenko Kapović and Borut Peterlin. "Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients." European Neurology 57, no. 4 (2007): 203-207. https://urn.nsk.hr/urn:nbn:hr:184:786338

Ristić, S., et al. (2007) 'Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients', European Neurology, 57(4), pp. 203-207. Available at: https://urn.nsk.hr/urn:nbn:hr:184:786338 (Accessed 22 November 2024)

Ristić S, Lovrečić L, Starčević Čizmarević N, Brajenović Milić B, Šega Jazbec S, Sepčić J, and sur.. Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients. European Neurology [Internet]. 2007 [cited 2024 November 22];57(4):203-207. Available at: https://urn.nsk.hr/urn:nbn:hr:184:786338

S. Ristić, et al., "Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients", European Neurology, vol. 57, no. 4, pp. 203-207, 2007. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:786338. [Accessed: 22 November 2024]

Metadata
Title (english)Tumor Necrosis Factor-alpha-308 Gene Polymorphism in Croatian and Slovenian Multiple Sclerosis Patients
AuthorSmiljana Ristić
MBZ: 142283
AuthorLuca Lovrečić
AuthorNada Starčević-Čizmarević
AuthorBojana Brajenović-Milić
AuthorSaša Šega Jazbec
AuthorJuraj Sepčić
AuthorMiljenko Kapović
AuthorBorut Peterlin
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Neurology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Previous findings regarding the role of TNF-a-308 gene polymorphism in multiple sclerosis (MS) are contradictory.This study's aim was to investigate the possible influence of TNF-a-308 polymorphism on MS susceptibility and MS disease process in a Croatian and Slovenian population. Genotyping was performed in 338 patients and 460 healthy controls. The TNF2 allele was present in 123 (26.8%) of healthy controls versus 67 (19.9%) of MS patients (p=0.023, odds ratio=0.68, 95% confidence interval=0.48-0.95), suggesting that carriage of the TNF2 allele might decrease MS risk. The difference of TNF2-allele carrier frequency between patients and controls was identified in relapsing-remitting (RR) MS group.There was no association between TNF2-allele carrier status and age at disease onset or disease progression. Our results suggest that in the study populations the TNF-a-308 polymorphism may play a role in MS susceptibility.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleEuropean Neurology
Numberingvol. 57, no. 4, pp. 203-207
p-ISSN0014-3022
URN:NBNurn:nbn:hr:184:786338
Publication2007
ProjectNumber: 062-1962766-0470
Title (croatian): Genetička analiza multiple skleroze
Leader: Smiljana Ristić
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://bib.irb.hr/318947
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 3.0 Unported (CC BY 3.0) icon
Created on2019-03-05 11:27:07