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Scientific paper - Original scientific paper
Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients
Kidney and Blood Pressure Research, 39 (2014), 4; 308-314. https://doi.org/10.1159/000355808
Mikolašević, Ivana; Rački, Sanjin; Zaputović, Luka; Lukenda, Vesna; Sladoje-Martinović, Branka; Orlić, Lidija

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Mikolašević, I., Rački, S., Zaputović, L., Lukenda, V., Sladoje Martinović, B. & Orlić, L. (2014). Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients. Kidney and Blood Pressure Research, 39. (4), 308-314. doi: 10.1159/000355808

Mikolašević, Ivana, et al. "Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients." Kidney and Blood Pressure Research, vol. 39, no. 4, 2014, pp. 308-314. https://doi.org/10.1159/000355808

Mikolašević, Ivana, Sanjin Rački, Luka Zaputović, Vesna Lukenda, Branka Sladoje Martinović and Lidija Orlić. "Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients." Kidney and Blood Pressure Research 39, no. 4 (2014): 308-314. https://doi.org/10.1159/000355808

Mikolašević, I., et al. (2014) 'Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients', Kidney and Blood Pressure Research, 39(4), pp. 308-314. doi: 10.1159/000355808

Mikolašević I, Rački S, Zaputović L, Lukenda V, Sladoje Martinović B, Orlić L. Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients. Kidney and Blood Pressure Research [Internet]. 2014 [cited 2024 May 06];39(4):308-314. doi: 10.1159/000355808

I. Mikolašević, S. Rački, L. Zaputović, V. Lukenda, B. Sladoje Martinović and L. Orlić, "Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients", Kidney and Blood Pressure Research, vol. 39, no. 4, pp. 308-314, 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:119311. [Accessed: 06 May 2024]

Metadata
Title (english)Nonalcoholic Fatty Liver Disease (NAFLD) And Cardiovascular Risk In Renal Transplant Recipients
AuthorIvana Mikolašević
AuthorSanjin Rački
AuthorLuka Zaputović
AuthorVesna Lukenda
AuthorBranka Sladoje-Martinović
AuthorLidija Orlić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background/Aims: Renal transplant recipients (RTRs) are at high risk for cardiovascular (CVD) mortality. Recently, nonalcoholic fatty liver disease (NAFLD) has been recognized as a new risk factor for adverse CVD events in the general population. We examined whether transient elastography (TE) defined NAFLD was associated with atherosclerosis in RTRs, as measured by ultrasound in the carotid arteries. Methods: Carotid atherosclerosis was assesses in 71 RTRs with a TE proven NAFLD. With the help of TE liver stiffness was used to assess liver fibrosis and Controlled Attenuation Parameter (CAP) was used to detect and quantify liver steatosis. NAFLD was defined by the presence of steatosis with CAP values ≥238 dB.m-1. Results: RTRs with NAFLD showed more carotid atherosclerosis than RTRs without NAFLD. RTRs-NAFLD patients had the mean intima-media measurements (ITM) of 1.1±0.1 mm and that was statistically significant higher than the mean ITM founded in RTRs without NAFLD (1.1±0.1 vs. 0.9±0.1 mm; p<0.0001). Furthermore, RTRs-NAFLD patients had statistically significant higher prevalence of plaques in comparison with RTRs without NAFLD (p=0.021). Conclusion: We showed for the first time that carotid atherosclerosis is advanced in RTRs with NAFLD. Detection of NAFLD by TE should alert to the existence of an increased cardiovascular risk in RTRs.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleKidney and Blood Pressure Research
Numberingvol. 39, no. 4, pp. 308-314
p-ISSN1420-4096
e-ISSN1423-0143
DOIhttps://doi.org/10.1159/000355808
URN:NBNurn:nbn:hr:184:119311
Publication2014
Publication2014-09-19
Document URLhttps://www.karger.com/Article/FullText/355808
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) icon
Created on2019-03-13 15:36:54