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Scientific paper - Original scientific paper
Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle
Collegium antropologicum, 36 (2012), 1; 167-172. urn:nbn:hr:184:678692
Bajek, Snježana; Nikolić, Marina; Šoić-Vranić, Tamara; Bajek, Goran; Cvijanović, Olga; Starčević-Klasan, Gordana

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Bajek, S., Nikolić, M., Šoić Vranić, T., Bajek, G., Cvijanović, O. & Starčević Klasan, G. (2012). Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle. Collegium antropologicum, 36. (1), 167-172. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:678692

Bajek, Snježana, et al. "Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle." Collegium antropologicum, vol. 36, no. 1, 2012, pp. 167-172. https://urn.nsk.hr/urn:nbn:hr:184:678692

Bajek, Snježana, Marina Nikolić, Tamara Šoić Vranić, Goran Bajek, Olga Cvijanović and Gordana Starčević Klasan. "Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle." Collegium antropologicum 36, no. 1 (2012): 167-172. https://urn.nsk.hr/urn:nbn:hr:184:678692

Bajek, S., et al. (2012) 'Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle', Collegium antropologicum, 36(1), pp. 167-172. Available at: https://urn.nsk.hr/urn:nbn:hr:184:678692 (Accessed 02 September 2024)

Bajek S, Nikolić M, Šoić Vranić T, Bajek G, Cvijanović O, Starčević Klasan G. Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle. Collegium antropologicum [Internet]. 2012 [cited 2024 September 02];36(1):167-172. Available at: https://urn.nsk.hr/urn:nbn:hr:184:678692

S. Bajek, M. Nikolić, T. Šoić Vranić, G. Bajek, O. Cvijanović and G. Starčević Klasan, "Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle", Collegium antropologicum, vol. 36, no. 1, pp. 167-172, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:678692. [Accessed: 02 September 2024]

Metadata
Title (english)Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle
AuthorSnježana Bajek
AuthorMarina Nikolić
AuthorTamara Šoić-Vranić
AuthorGoran Bajek
AuthorOlga Cvijanović
AuthorGordana Starčević-Klasan
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Neurosurgery)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Anatomy
Abstract (english)
The aim of this study was to determine whether hyperbaric oxygen (HBO2) treatment influences the expression of transcriptional myogenic factors in denervated rat’s extensor digitorum longus muscle. Thus, expressing regulatory myogenic factors MyoD and myogenin were analyzed in denervated muscles (up to 30 days). Second group of denervated rats were afterwards treated with HBO2. Normal, innervated muscles were used as controls. Western blot analysis showed a significant upregulation of MyoD and myogenin proteins in denervated muscle during this period. Denervated muscles of rats exposed to HBO2 treatment had also significant upregulation of both transcriptional factors but the treatment had not altered their expression. The immunohistochemical analysis showed MyoD and myogenin protein expression through this period in the denervated, untreated muscles and in denervated muscles of rats treated with HBO2, too. One month denervation caused a reduction in muscle fiber cross-sectional area. The treatment with HBO2 had not reduced the degree of atrophy. The protocol of hyperbaric oxygenation (HBO) applied in this study had no beneficial effect either on transcriptional myogenic factors or on atrophy of denervated rat muscle.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 36, no. 1, pp. 167-172
p-ISSN0350-6134
URN:NBNurn:nbn:hr:184:678692
Publication2012
ProjectNumber: 062-0000000-1352
Title (croatian): Utjecaj hiperbarične oksigenacije na regeneraciju skeletnog mišića i živca
Leader: Snježana Bajek
Jurisdiction: Croatia
Funding stream: ZP
ProjectNumber: 062-0620529-0517
Title (croatian): Regeneracija mozga, perifernog živca i skeletnog mišića u šećernoj bolesti
Leader: Romana Jerković
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttps://hrcak.srce.hr/78808
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2019-04-15 13:36:34