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Scientific paper - Review paper
Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema
Medicina Fluminensis, 55 (2019), 2; 142-147. urn:nbn:hr:184:522030
Bilen Babić, Marijana; Merlak, Maja; Gržetić-Lenac, Renata; Valković Antić, Ivana; Grubešić, Petra

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Bilen Babić, M., Merlak, M., Gržetić Lenac, R., Valković Antić, I. & Grubešić, P. (2019). Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema. Medicina Fluminensis, 55. (2), 142-147. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:522030

Bilen Babić, Marijana, et al. "Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema." Medicina Fluminensis, vol. 55, no. 2, 2019, pp. 142-147. https://urn.nsk.hr/urn:nbn:hr:184:522030

Bilen Babić, Marijana, Maja Merlak, Renata Gržetić Lenac, Ivana Valković Antić and Petra Grubešić. "Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema." Medicina Fluminensis 55, no. 2 (2019): 142-147. https://urn.nsk.hr/urn:nbn:hr:184:522030

Bilen Babić, M., et al. (2019) 'Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema', Medicina Fluminensis, 55(2), pp. 142-147. Available at: https://urn.nsk.hr/urn:nbn:hr:184:522030 (Accessed 20 May 2024)

Bilen Babić M, Merlak M, Gržetić Lenac R, Valković Antić I, Grubešić P. Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema. Medicina Fluminensis [Internet]. 2019 [cited 2024 May 20];55(2):142-147. Available at: https://urn.nsk.hr/urn:nbn:hr:184:522030

M. Bilen Babić, M. Merlak, R. Gržetić Lenac, I. Valković Antić and P. Grubešić, "Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema", Medicina Fluminensis, vol. 55, no. 2, pp. 142-147, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:522030. [Accessed: 20 May 2024]

Metadata
Title (croatian)Nesteroidni protuupalni lijekovi u liječenju cistoidnog makularnog edema
Title (english)Nonsteroidal antiinflammatory drugs and treatment of cystoid macular edema
AuthorMarijana Bilen Babić https://orcid.org/0000-0003-3853-6794
Department of Ophthalmology, Clinical Hospital Center Rijeka, Rijeka, Croatia
AuthorMaja Merlak
Department of Ophthalmology, Clinical Hospital Center Rijeka, Rijeka, Croatia
AuthorRenata Gržetić-Lenac
Department of Ophthalmology, Clinical Hospital Center Rijeka, Rijeka, Croatia
AuthorIvana Valković Antić
Department of Ophthalmology, Clinical Hospital Center Rijeka, Rijeka, Croatia
AuthorPetra Grubešić
Department of Ophthalmology, Clinical Hospital Center Rijeka, Rijeka, Croatia
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Ophthalmology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
Abstract (croatian)
Nesteroidni protuupalni lijekovi (NSAID, engl. nonsteroidal antiinflammatory drugs) postali su značajna dodatna terapija u rutinskim i kompliciranim intraokularnim operacijama. Topički NSAID-i sprječavaju intraoperativnu miozu, smanjuju bol, postoperativnu upalu i učestalost cistoidnog makularnog edema (CME). Iako nema uspostavljenog protokola za profilaksu pseudofakičnog CME-a, zbog veze između proupalnih prostaglandina i CME-a primjena topičkih kortikosteroida i topičkih NSAID-a može spriječiti CME. NSAID-i imaju sinergistički protuupalni učinak sa steroidima, ali se mogu upotrijebiti i sami kada bi kortikosteroidna terapija mogla biti rizična. Zbog njihovog snažnog utjecaja na prevenciju perioperativnih komplikacija potrebna su prospektivna klinička istraživanja za definiranje protokola terapijske primjene topičkih NSAID-a.
Abstract (english)
Nonsteroidal antiinflammatory drugs (NSAIDs) have become a significant therapeutic adjunctive tool in the routine and complicated intraocular surgery. Topical NSAIDs prevent intraoperative miosis, reduce pain, postoperative inflammation and incidence of cystoid macular edema (CME). Although there is no established protocol for prophylaxis of pseudophakic CME, due to the relationship between proinflammatory prostaglandins and CME, using corticosteroids and NSAIDs could prevent CME. NSAIDs have a synergistic antiinflammatory effect with steroids, but can also be used alone when corticosteroid therapy could be harmful. Prospective clinical trials need to define treatment protocol for topical NSAIDs use, due to their powerful influence to prevent perioperative complications.
Keywords (croatian)
Keywords (english)
Languagecroatian
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis
Numberingvol. 55, no. 2, pp. 142-147
p-ISSN1847-6864
e-ISSN1848-820X
URN:NBNurn:nbn:hr:184:522030
Publication2019
Document URLhttps://hrcak.srce.hr/218802
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2019-06-13 12:05:38