Inflammatory bowel disease, Crohn's disease and ulcerative colitis, indicate the immune conditions resulting from the interaction of intestinal mucosa and intestinal bacteria in genetically predetermined individuals. The main characteristic of both diseases is a chronic recurrent course, and what differentiates them is the place of occurrence and extent of involvement of the tissue. While ulcerative colitis affects the rectum and colon, Crohn's disease occurs in any part of the digestive tract in the form of discontinuous inflammatory changes. Both diseases are characterized by chronic inflammation of the gastrointestinal mucosa and accompanied by numerous extraintestinal manifestations. Oral manifestations of inflammatory bowel diseases can be divided into specific, which include the occurrence of non-caseous granulomas occurring only in Crohn's disease, while only non-specific lesions are described in ulcerative colitis. Specific lesions are: mucosal tags, cobblestoning, mucogingivitis, orofacial edema and deep linear ulcerations. They occur mostly on the buccal mucosa, vestibule, retromolar area, lips and gingiva. The most notable non-specific lesions are aphtous stomatitis and pyostomatitis vegetans. Angular cheilitis, glossitis and caries may also appear. Patients can experience lesions due to malnutrition, and as a side effect of medication. Orofacial granulomatosis is a clinical condition that describes patients with the same oral manifestations as with Crohn's disease, but without any intestinal disease. The aim of the treatment of oral lesions in patients with inflammatory bowel diseases is to reduce pain, accelerate the healing of lesions, and prevent secondary infections. Therapy is directed to the treatment of the underlying disease. Patients with inflammatory bowel disease are, among other, on immunosuppressive and corticosteroid therapy, therefore caution is needed in dental treatment