prikaz prve stranice dokumenta Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report
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Scientific paper - Case study
Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report
Clinics and Practice, 9 (2019), 2; 58-60. https://doi.org/10.4081/cp.2019.1157
Vučinić, Damir; Zahirović, Dag; Manestar, Dubravko; Belac-Lovasić, Ingrid; Braut, Tamara; Kovač, Leo; Jonjić, Nives; Zamolo, Gordana

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Vučinić, D., Zahirović, D., Manestar, D., Belac Lovasić, I., Braut, T., Kovač, L. ... Zamolo, G. (2019). Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report. Clinics and Practice, 9. (2), 58-60. doi: 10.4081/cp.2019.1157

Vučinić, Damir, et al. "Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report." Clinics and Practice, vol. 9, no. 2, 2019, pp. 58-60. https://doi.org/10.4081/cp.2019.1157

Vučinić, Damir, Dag Zahirović, Dubravko Manestar, Ingrid Belac Lovasić, Tamara Braut, Leo Kovač, Nives Jonjić and Gordana Zamolo. "Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report." Clinics and Practice 9, no. 2 (2019): 58-60. https://doi.org/10.4081/cp.2019.1157

Vučinić, D., et al. (2019) 'Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report', Clinics and Practice, 9(2), pp. 58-60. doi: 10.4081/cp.2019.1157

Vučinić D, Zahirović D, Manestar D, Belac Lovasić I, Braut T, Kovač L, and sur.. Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report. Clinics and Practice [Internet]. 2019 June 11 [cited 2024 May 05];9(2):58-60. doi: 10.4081/cp.2019.1157

D. Vučinić, et al., "Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report", Clinics and Practice, vol. 9, no. 2, pp. 58-60, June 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:426895. [Accessed: 05 May 2024]

Metadata
Title (english)Recurrent amelanotic melanoma of nasal cavity: Biological variability and unpredictable behavior of mucosal melanoma. A case report
AuthorDamir Vučinić
AuthorDag Zahirović
AuthorDubravko Manestar
AuthorIngrid Belac-Lovasić
AuthorTamara Braut
AuthorLeo Kovač
AuthorNives Jonjić
AuthorGordana Zamolo
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Otorhinolaryngology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Radiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of this report is to present a case of a patient with a recurrent nasal cavity amelanotic melanoma (AM), with emphasis on diagnosis and therapy options of this clinical entity. A 65-year-old female patient presented with pain in the right cheek region and nasal obstruction. In 2013, she was diagnosed with mucosal melanoma (MM) of the left nasal cavity. After endoscopic surgery and radiotherapy, the patient was followed by the oncology team. Five years after the initial diagnosis, rhinoscopy showed a tumorous formation in the right nasal cavity. The tumor mass was without black discoloration and was the same color as the surrounding nasal mucosa. Microscopic examination after biopsy of the tumor confirmed amelanotic MM. The patient underwent an additional endoscopic surgery. A complete standard diagnostic workup for MM found metastases in head and neck lymph nodes, on both sides. MMs of head and neck are uncommon malignancies. Unique biology of MM cells causes a high rate of recurrences. This report presents an example of recurrent AM of the nasal cavity, in treatment with checkpoint inhibitor (pembrolizumab), which could provide a good therapy option for patients with MM.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleClinics and Practice
Numberingvol. 9, no. 2, pp. 58-60, 1157
p-ISSN2039-7275
e-ISSN2039-7283
DOIhttps://doi.org/10.4081/cp.2019.1157
URN:NBNurn:nbn:hr:184:426895
Publication2019-06-11
Document URLhttps://www.clinicsandpractice.org/index.php/cp/article/view/1157
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2019-11-21 19:08:31