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master's thesis
NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI
Rijeka: University of Rijeka, Faculty of Medicine, 2019. urn:nbn:hr:184:280240
Depolo, Toni
University of Rijeka
Faculty of Medicine
Department of Neurology

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Depolo, T. (2019). NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:280240

Depolo, Toni. "NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI." Master's thesis, University of Rijeka, Faculty of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:184:280240

Depolo, Toni. "NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI." Master's thesis, University of Rijeka, Faculty of Medicine, 2019. https://urn.nsk.hr/urn:nbn:hr:184:280240

Depolo, T. (2019). 'NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:280240

Depolo T. NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2019 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:184:280240

T. Depolo, "NEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:184:280240

Metadata
TitleNEMOTORIČKI SIMPTOMI NAKON DBS TERAPIJE BOLESNIKA S PARKINSONOVOM BOLESTI
Title (english)NON-MOTOR SYMPTOMS AFTER DBS THERAPY OF PATIENTS ITH PARKINSON´S DISEASE
AuthorToni Depolo
MentorVladimira Vuletić (mentor)
Committee memberMira Bučuk (predsjednik povjerenstva)
Committee memberOlivio Perković (član povjerenstva)
Committee memberSvjetlana Grbac-Ivanković (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Neurology)
Rijeka
Defense date and country2019-09-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract
PB je dosta kompleksna bolest. Utjecana je od strane velikog broja rizičnih faktora, no još uvijek joj se ne zna pravi uzrok. Prije nastupa same bolesti prethodi joj prodromalna faza u kojoj dominiraju NMS. PB čine i MS i NMS, a sama bolest zahvaća podosta šire neuroanatomsko područje no što se to prije mislilo, te se danas zna da PB ima puno opširniju kliničku sliku, no što se o njoj spominje u djelu dr. Parkinsona. Ova bolest predstavlja veliki izazov kako za bolesnika, tako i za bolnički tim. Nažalost temelj dijagnostike je još uvijek klinički kriterij, slikovne metode nam koliko toliko pomažu u diferencijalnoj dijagnostici, a na pravi biomarker bolesti se još uvijek čeka. Terapijski odgovor levodope i ostalih antiparkinsonika nakon nekoliko godina jenjava. Iako PB nema izliječenja, zahvaljujući suvremenoj terapiji, životni vijek oboljelih je vrlo sličan onome koji je i kod zdrave populacije, te kvaliteta života oboljelih je znatno poboljšana u odnosu na kojoj je razini bila prije ere antiparkinsonika. DBS se može smatrati još jednom prekretnicom koja poboljšava kvalitetu života oboljelih od PB, i to upravo onih bolesnika koji se nalaze u jako uznapredovaloj fazi bolesti.
Abstract (english)
Parkinsons disease (PD) is quite a complex disease. It is influenced by a huge variety of risk factors, but we still don't know the true cause of it. Before the onset of the disease itself, it is preceded by a prodromal phase dominated by NMS. PD is comprised of MS and NMS, and the disease itself covers a much broader neuroanatomical area than previously thought, and it is nowadays known that PD has a much broader clinical picture than it is mentioned in Dr. Parkinson's work. This disease presents a great challenge for both the patient and the medical team. Unfortunately, the basis of diagnostics is still the clinical criteria, imaging methods are of minimal help with differential diagnosis, and we are still waiting on the discovery of the true biomarker of this disease. The therapeutic response of levodopa and other antiparkinsonics reduces with time. Although PD has no cure, but thanks to modern therapy, the life expectancy of patients is very similar to that of a healthy population, and the quality of life of patients is much improved compared to what it was before the antiparkinsonics era. DBS can be considered as another milestone that improves the quality of life of patients with PD, particularly those patients who are in a very advanced stage of the disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:280240
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-01-15 08:22:57