Title FOTOKATALITIČKO ANTIBAKTERIJSKO DJELOVANJE CINKOVOG OKSIDA NA POLIMERNOM NOSAČU Title (english) PHOTOCATALYTIC ANTIBACTERIAL EFFECT OF ZINC OXIDE ON POLYMER CARRIER Author Silvestar Mežnarić Mentor Ivana Gobin (mentor)Committee member Gordana Žauhar (predsjednik povjerenstva)Committee member Vanja Vasiljev (član povjerenstva)Committee member Ivana Gobin (član povjerenstva)Granter University of Rijeka Defense date and country 2019-09-06, Croatia Scientific / art field, BIOMEDICINE AND HEALTHCARE Scientific / art field, BIOMEDICINE AND HEALTHCARE Abstract Dezinfekcija kao pojam poznata je još od starog vijeka te je ljudima služila kao prevencija i borba protiv uzročnika zaraznih bolesti. Metode oksidativnog tretiranja vode klorom i spojevima klora naišle su na prepreku zbog novih saznanja koje govore o štetnosti klora za ljude i okoliš, dok su novije metode poput korištenja ozona skupe i zahtijevaju razvoj tehnologije. Korištenje ionizirajućeg zračenja, također ostavlja negativne posljedice za okoliš. Među svim ograničenjima, potrebno je okrenuti se ka novim metodama koje zahtijevaju razvoj „zelene“ metodologije, no pokazuju svoj veliki potencijal, što u dezinfekcijskom smislu, to i u ekonomskom smislu. Jedna takva metoda je svakako korištenje ultraljubičastog zračenja, neionizirajuće zračenje koje ima antibakterijski učinak, ne ostavlja rezidue, ne šteti okolišu i ne zahtijeva veliku zaštitu radnika i skupu tehnološku prilagodbu. Takva metoda isto ima svoja ograničenja, a na trenutnoj generaciji je da prijeđe preko tih ograničenja kombinacijom različitih metoda te tako nastavi dobru higijensku praksu koju je čovječanstvo kroz povijest usavršavalo. U ovom radu ispitivana su antibakterijska svojstva cinkovog oksida na polimernom nosaču u kombinaciji sa UV - A zračenjem. S apsorpcijom ultraljubičastog zračenja se aktivira cinkov oksid stvarajući reaktivne oksidativne hidroksidne radikale i peroksid koji bakterijsku stanicu izlažu oksidativnom stresu i inaktiviraju je, s druge strane UV zračenje oštećuje genetski sadržaj bakterije te njene popravne mehanizme. Ispitivanje je vršeno na Medicinskom fakultetu Sveučilišta u Rijeci u suradnji sa Sveučilištem u Rijeci, Odjelom za fiziku u okviru projekta Hrvatske zaklade za znanost „Priprema poroznih tankoslojnih materijala za pročišćavanje vode koristeći tehniku Depozicije atomskih slojeva (ALD)“ (IP-2016-06-3568). Istraživanja su pokazala da cinkov oksid na polimernom nosaču u kombinaciji sa UV zračenjem pokazuje fotoinaktivacijska antibakterijska svojstva već nakon 15 – 30 minuta osvjetljavanja te uz daljnja istraživanja ima veliki potencijal postati učinkoviti supstrat za dezinfekciju vode.
Abstract (english) Disinfection as a term has been known since ancient times and has served humans as a prevention and control of infectious diseases. Methods of treating water with chlorine and chlorine compounds have been hampered by new findings that talk about chlorine damage to humans and the environment, newer methods such as ozone are expensive and require technology development, the use of ionizing radiation also leaves negative environmental impacts. Due to above-mentioned limitations, it is necessary develop new „green“ methodologies having a great potential, both in disinfecting and economic terms. Such methods involve also ultraviolet irradiation, a non-ionizing radiation that has an antibacterial effect, does not leave residues, does not harm the environment and does not require great worker protection and expensive technological adaptation. Such a method shows some limitations as well, and it is up to the current generation to go beyond these constraints with new products and technologies with improved performances, thus continuing the good hygiene practices that humanity has perfected throughout history. In this thesis, the antibacterial properties of zinc oxide on a polymer support in combination with UV - A radiation were investigated. The activation of zinc oxide by photoabsorbtion of ultraviolet radiation activates zinc oxide, thus producing reactive oxidative hydroxy radicals and peroxide, which expose the bacterial cell to oxidative stress and inactivate it, while the UV radiation itself damages the genetic content of the bacterium and its repair mechanisms. The study was performed at the Faculty of Medicine, University of Rijeka in cooperation with the University of Rijeka, Department of Physics, and was financially supported by the Croatian Science Foundation under project “Preparation of Porous Thin-film Materials for Water Purification using Atomic Layer Deposition (ALD) “(IP-2016-06-3568).
Our studies showed that zinc oxide on a polymer carrier in combination with UV irradiation exhibits photoinactivation antibacterial properties after 15 - 30 minutes of illumination,showing a great potential of this material to be used as an effective substrate in water disinfection.
Keywords
dezinfekcija vode
Keywords (english)
Water Purification
Language croatian URN:NBN urn:nbn:hr:184:251186 Study programme Title: Study of Sanitary Engineering Type of resource Text File origin Born digital Access conditions Open access Terms of use Created on 2020-01-24 16:47:15
