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Professional paper - Review paper
Treatment of Vulvar Cancer
Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 21 (2012), 2; 55-61. urn:nbn:hr:184:509425
Haller, Herman; Krašević, Maja; Rupčić, Stanislav; Brnčić-Fischer, Alemka; Perović, Danko; Eminović, Senija; Klarić, Marko

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Haller, H., Krašević, M., Rupčić, S., Brnčić Fischer, A., Perović, D., Eminović, S. & Klarić, M. (2012). Treatment of Vulvar Cancer. Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 21. (2), 55-61. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:509425

Haller, Herman, et al. "Treatment of Vulvar Cancer." Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, vol. 21, no. 2, 2012, pp. 55-61. https://urn.nsk.hr/urn:nbn:hr:184:509425

Haller, Herman, Maja Krašević, Stanislav Rupčić, Alemka Brnčić Fischer, Danko Perović, Senija Eminović and Marko Klarić. "Treatment of Vulvar Cancer." Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics 21, no. 2 (2012): 55-61. https://urn.nsk.hr/urn:nbn:hr:184:509425

Haller, H., et al. (2012) 'Treatment of Vulvar Cancer', Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, 21(2), pp. 55-61. Available at: https://urn.nsk.hr/urn:nbn:hr:184:509425 (Accessed 04 May 2024)

Haller H, Krašević M, Rupčić S, Brnčić Fischer A, Perović D, Eminović S, and sur.. Treatment of Vulvar Cancer. Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics [Internet]. 2012 [cited 2024 May 04];21(2):55-61. Available at: https://urn.nsk.hr/urn:nbn:hr:184:509425

H. Haller, et al., "Treatment of Vulvar Cancer", Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, vol. 21, no. 2, pp. 55-61, 2012. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:509425. [Accessed: 04 May 2024]

Metadata
Title (english)Treatment of Vulvar Cancer
Title (croatian)Liječenje raka stidnice
AuthorHerman Haller
AuthorMaja Krašević
AuthorStanislav Rupčić
AuthorAlemka Brnčić-Fischer
AuthorDanko Perović
AuthorSenija Eminović
AuthorMarko Klarić
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
Objective. Treatment modalities for vulvar cancer includes: surgical, radio- and chemo-therapeutical options. In this paper we discuss the impact of new staging classification (2009) on the treatment modalities. Methods. We reviewed the available literature on treatment of invasive vulvar cancer and compared with own results on 114 squamous vulvar cancer patients. Results. The cornerstone of primary treatment remains surgery. There is a trend to introduce less radical surgery, especially in early disease (wide excision). In patients with advanced primary disease, treatment criteria for the use of chemo/radiotherapy are still not completely defined. Conclusions. Less radical approach in surgical management of early stages with implementation of sentinel node identification techniques, the use of triple incision in radical vulvectomy decrease treatment associated morbidity with similar outcome results. Advanced disease requires individualized approach including combination of chemoradiation option and surgery associated with increased complication rate and undefined benefit in final outcome. The centralization of cases will facilitate the use of optimal treatment and patient recruitment for clinical studies. Finally, a new staging system adopted in 2009 whould be applied in all cases with invasive vulvar cancer.
Abstract (croatian)
Cilj. U liječenju raka stidnice koriste se kirurška terapija, radioterapija i kemoterapija odnosno njihove razne kombinacije. Cilj ovog članka je istražiti i prikazati utjecaj nove klasifikacije (FIGO 2009.) na liječidbeni postupak raka stidnice. Metode. Pregledali smo dostupnu literaturu o liječenju invazivnog raka stidnice i usporedili s našim rezultatima na uzorku od 114 bolesnica sa skvamoznim rakom stidnice. Rezultati. Temelj primarnog liječenja je i dalje kirurški zahvat. Postoji težnja da se smanji radikalitet kirurških postupaka, poglavito u ranom stadiju bolesti (široka ekscizija). U bolesnica s uznapredovalom bolešću kriteriji za primjenu kemo/radioterapije još uvijek nisu jasno definirani. Zaključak. Manje radikalan kirurški pristup u liječenju ranih stadija bolesti, uvođenje metoda identifikacije limfnog čvora čuvara, te primjena tri separatna reza pri radikalnoj vulvektomiji smanjili su morbiditet kao posljedicu liječenja bolesti, bez bitnih promjena u ishodu samog liječenja. Bolesnice s uznapredovalom bolešću zahtijevaju individualizirani pristup uključujući kombinaciju kemoiradijacije i kirurgije povezane s povećanom stopom komplikacija i nejasnom korisnošću što se tiče završnog ishoda liječenja. Centralizacija bolesnica s rakom stidnice omogućit će primjenu optimalnog liječenja i dostupnost bolesnica za kliničke studije. Na kraju, nova FIGO klasifikacija bolesti iz 2009. godine trebala bi se koristiti u svim slučajevima invazivnog raka stidnice.
Keywords (english)
Keywords (croatian)
Languageenglish
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleGynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics
Numberingvol. 21, no. 2, pp. 55-61
p-ISSN1330-0091
URN:NBNurn:nbn:hr:184:509425
Publication2012
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-20 08:02:38