Title ULTRAZVUČNO VOĐENA ŠIROKOIGLENA BIOPSIJA DOJKE
Title (english) LTRASOUND-GUIDED CORE NEEDLE BREAST BIOPSY
Author Petra Smeh
Mentor Petra Valković Zujić (mentor)
Committee member Damir Miletić (predsjednik povjerenstva)
Committee member Manuela Avirović (član povjerenstva)
Committee member Damir Grebić (član povjerenstva)
Granter University of Rijeka Faculty of Medicine (Department of Radiology) Rijeka
Defense date and country 2020-07-17, Croatia
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Radiology
Scientific / art field, discipline and subdiscipline BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Pathology
Abstract Karcinom dojke predstavlja najčešće sijelo karcinoma i vodeći je uzrok smrti u žena. Rizik od karcinoma dojke raste sa dobi. Poznavanje patoloških lezija u dojci od iznimne je važnosti kako bi se moglo što prije započeti s praćenjem ili liječenjem pacijentica. Lezije u dojci mogu se podijeliti na benigne i maligne lezije. Dijagnostiku patologije dojke, nakon sistematske anamneze i fizikalnog pregleda, slijede slikovne metode kojima ćemo pobliže znati o kakvoj se leziji radi. Glavna metoda otkrivanja malignih lezija je mamografija. Naposljetku, odlučiti ćemo se i za moguće citološke i patohistološke metode. Perkutana biopsija osnovna je metoda u dijagnostici sumnjivih lezija dojke. Temeljni cilj perkutane biopsije (engl., core needle biopsy, CNB) je da se vidljiva ili suspektna lezija nađena radiološkim metodama ili fizikalnim pregledom pošalje na patohistološku analizu kako bi došli do konačne dijagnoze, ali i da izbjegnemo kirurški zahvat moguće benigne lezije i ne izlažemo pacijenticu većem stresnom čimbeniku. Ultrazvuk je metoda izbora za nadzor vođenja biopsija jer je jednostavna, najbrža i najmanje štetna za pacijente. Jedine apsolutne kontraindikacije su odbijanje intervencije i lezija koja se ne vidi na prisutnom UZV. Najčešće se javlja malena bolnost u području biopsije, a rijetke komplikacije koje se mogu pojaviti su hematom ili infekcija. U 2 % slučajeva široko iglene biopsije, iako je manja učestalost u odnosu na ostale metode, dolazi do lažno negativnih rezultata. Širokoiglena biopsija je dovoljno vrijedna i dostatna metoda za točnu dijagnozu.
Abstract (english) Globally, breast cancer is the most frequently diagnosed malignancy and the leading cause of cancer death in women. The risk of breast cancer increases with older age. Knowledge of pathological lesions in the breast is extremely important in order to begin monitoring or treatment of patients as soon as possible. Breast lesions can be divided into benign and malignant lesions. The diagnosis of breast pathology, after a systematic anamnesis and physical examination, is followed by imaging methods by which we will know in more detail what kind of lesion it is. The main method of detecting malignant lesions is mammography. Finally, we will decide on possible cytological and pathohistological methods. Percutaneous breast biopsy is widely practised to evaluate suspicious breast lesions. The primary goal of core needle biopsy (CNB) is to send a visible or suspicious lesion found by radiological methods or physical examination for pathohistological analysis to arrive at a definitive diagnosis, but also to avoid surgery for possible benign lesions and not expose the patient to a major stressor. Ultrasound is the method of choice for guiding biopsy management because it is simple, fastest, and least harmful to patients. The only absolute contraindications are refusal of intervention and lesions that are not visible on the present ultrasound. Minor pain in the biopsy area is most common and rare complications that may occur are hematoma or infection. In 2 % of cases of wide-needle biopsy, although the frequency is lower compared to other methods, false negative results can occur. Wide-needle biopsy is a sufficiently valuable and sufficient method for accurate diagnosis.
Keywords
karcinom dojke
lezije dojke
perkutana biopsija
ultrazvuk
patohistološka analiza
Keywords (english)
breast cancer
breast lesions
core needle biopsy
ultrasound
pathohistological analysis
Language croatian
URN:NBN urn:nbn:hr:184:588062
Study programme Title: Medicine Study programme type: university Study level: integrated undergraduate and graduate Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resource Text
File origin Born digital
Access conditions Open access
Terms of use
Created on 2020-11-23 09:56:19