Prostate cancer is the second leading cause of death among cancers. It is currently the most common cancer among the male population and 2.6 million new cases are diagnosed each year. The prostate is an odd organ located in the pelvis below the bladder. It is a glandular organ built of tubuloalveolar glands through which drainage channels open into the prostatic part of the urethra. For pathohistological diagnosis, we use two methods of prostate tumor classification, namely the Gleason scale and the TNM classification. The most common is adenocarcinoma of the epithelial cells of the peripheral tissue of the prostate. The Gleason scale refers to the degree of microscopically altered prostate cancer cells relative to normal prostate tissue. The clinical classification or TNM is staging cancer, ie the involvement of tissues and surrounding structures with cancer. The basic diagnostic procedures for diagnosing prostate cancer are DRP, PSA, TRUS, and prostate biopsy. In this retrospective study, an analysis of the medical records of 489 patients diagnosed and treated for prostate cancer at the Clinic of Urology, Clinical Hospital Center Rijeka in the period from 2013 to 2018 was conducted. The number of patients is increasing from year to year. Diagnostic criteria such as patient age, PSA, and Gleason zbroj follow expected values. Among the stages of operated patients, lower stages predominate, which is a good indicator of good clinical management