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Scientific paper - Preliminary note / Short communication
Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia
Archives of Virology, (2021); https://doi.org/10.1007/s00705-021-05029-7
Rokić, Filip; Trgovec-Greif, Lovro; Sučić, Neven; Čemeljić, Noa; Cekinović Grbeša, Đurđica; Svedružić, Željko; Rukavina, Tomislav; Vugrek, Oliver; Jurak, Igor

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Rokić, F., Trgovec Greif, L., Sučić, N., Čemeljić, N., Cekinović Grbeša, Đ., Svedružić, Ž. ... Jurak, I. (2021). Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia. Archives of Virology. doi: 10.1007/s00705-021-05029-7

Rokić, Filip, et al. "Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia." Archives of Virology, 2021. https://doi.org/10.1007/s00705-021-05029-7

Rokić, Filip, Lovro Trgovec Greif, Neven Sučić, Noa Čemeljić, Đurđica Cekinović Grbeša, Željko Svedružić, Tomislav Rukavina, Oliver Vugrek and Igor Jurak. "Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia." Archives of Virology (2021). https://doi.org/10.1007/s00705-021-05029-7

Rokić, F., et al. (2021) 'Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia', Archives of Virology. doi: 10.1007/s00705-021-05029-7

Rokić F, Trgovec Greif L, Sučić N, Čemeljić N, Cekinović Grbeša Đ, Svedružić Ž, and sur.. Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia. Archives of Virology [Internet]. 2021 March 24 [cited 2024 April 25]. doi: 10.1007/s00705-021-05029-7

F. Rokić, et al., "Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia", Archives of Virology, March 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:204942. [Accessed: 25 April 2024]

Metadata
Title (english)Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia
AuthorFilip Rokić
AuthorLovro Trgovec-Greif
AuthorNeven Sučić
AuthorNoa Čemeljić
AuthorĐurđica Cekinović Grbeša
AuthorŽeljko Svedružić
AuthorTomislav Rukavina
AuthorOliver Vugrek
AuthorIgor Jurak
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Social Medicine and Epidemiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Epidemiology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
We developed a next-generation SARS-CoV-2 sequencing platform and obtained the first SARS-CoV-2 sequences from patients in Croatia at the beginning of the COVID-19 outbreak in the spring of 2020. Integrating the sequencing and the epidemiological data, we show that patients were infected with different SARS-CoV-2 variants belonging to different clades (mostly G and GH). This result confirms that there was widespread virus transmission early in 2020. Interestingly, we identified a unique mutation resulting in a V13I substitution in Nsp5A, the main viral protease, in a patient who had not received antiviral therapy.
Keywords (english)
Languageenglish
Publication typeScientific paper - Preliminary note / Short communication
Publication statusAccepted
Peer reviewPeer review - international
Publication versionPublished version
Journal titleArchives of Virology
p-ISSN0304-8608
e-ISSN1432-8798
DOIhttps://doi.org/10.1007/s00705-021-05029-7
URN:NBNurn:nbn:hr:184:204942
Publication2021-03-24
Document URLhttp://link.springer.com/10.1007/s00705-021-05029-7
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2021-03-31 07:29:34