prikaz prve stranice dokumenta Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species
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Scientific paper - Review paper
Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species
International Journal of Molecular Sciences, 22 (2021), 10; 5274. https://doi.org/10.3390/ijms22105274
Strazic Geljic, Ivana; Kucan Brlic, Paola; Musak, Lucija; Karner, Dubravka; Ambriović-Ristov, Andreja; Jonjic, Stipan; Schu, Peter; Rovis, Tihana Lenac

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Strazic Geljic, I., Kucan Brlic, P., Musak, L., Karner, D., Ambriović Ristov, A., Jonjic, S. ... Rovis, T. L. (2021). Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species. International Journal of Molecular Sciences, 22. (10). doi: 10.3390/ijms22105274

Strazic Geljic, Ivana, et al. "Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species." International Journal of Molecular Sciences, vol. 22, no. 10, 2021. https://doi.org/10.3390/ijms22105274

Strazic Geljic, Ivana, Paola Kucan Brlic, Lucija Musak, Dubravka Karner, Andreja Ambriović Ristov, Stipan Jonjic, Peter Schu and Tihana Lenac Rovis. "Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species." International Journal of Molecular Sciences 22, no. 10 (2021). https://doi.org/10.3390/ijms22105274

Strazic Geljic, I., et al. (2021) 'Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species', International Journal of Molecular Sciences, 22(10). doi: 10.3390/ijms22105274

Strazic Geljic I, Kucan Brlic P, Musak L, Karner D, Ambriović Ristov A, Jonjic S, and sur.. Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species. International Journal of Molecular Sciences [Internet]. 2021 May 17 [cited 2024 November 08];22(10). doi: 10.3390/ijms22105274

I. Strazic Geljic, et al., "Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species", International Journal of Molecular Sciences, vol. 22, no. 10, May 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:195997. [Accessed: 08 November 2024]

Metadata
Title (english)Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species
AuthorIvana Strazic Geljic
AuthorPaola Kucan Brlic
AuthorLucija Musak
AuthorDubravka Karner
AuthorAndreja Ambriović-Ristov
AuthorStipan Jonjic
AuthorPeter Schu
AuthorTihana Lenac Rovis
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Center for Proteomics)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Histology and Embryology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Numerous viruses hijack cellular protein trafficking pathways to mediate cell entry or to rearrange membrane structures thereby promoting viral replication and antagonizing the immune response. Adaptor protein complexes (AP), which mediate protein sorting in endocytic and secretory transport pathways, are one of the conserved viral targets with many viruses possessing AP-interacting motifs. We present here different mechanisms of viral interference with AP complexes and the functional consequences that allow for efficient viral propagation and evasion of host immune defense. The ubiquity of this phenomenon is evidenced by the fact that there are representatives for AP interference in all major viral families, covered in this review. The best described examples are interactions of human immunodeficiency virus and human herpesviruses with AP complexes. Several other viruses, like Ebola, Nipah, and SARS-CoV-2, are pointed out as high priority disease-causative agents supporting the need for deeper understanding of virus-AP interplay which can be exploited in the design of novel antiviral therapies.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 22, no. 10, 5274
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms22105274
URN:NBNurn:nbn:hr:184:195997
Publication2021-05-17
ProjectNumber: IP-2020-02-6617
Title (croatian): Imunoregulatorna uloga proteina PrPC u imunološkom antivirusnom odgovoru i otpornosti na citomegalovirusnu infekciju
Acronym: PrImReg
Leader: Tihana Lenac Roviš
Jurisdiction: Croatia
Funding stream: IP
ProjectNumber: IP-2019-04-1577
Title (croatian): Integrin alpha V beta 5-povezane fokalne i retikularne adhezije u melanomu
Title (english): Integrin alpha V beta 5-associated Focal and Reticular Adhesions in Melanoma
Acronym: AdMeFoRe
Leader: Andreja Ambriović Ristov
Jurisdiction: Croatia
Funding stream: IP
ProjectNumber: uniri-biomed-18-233
Title (croatian): Međuodnos proteina PrPc i imunološkog sustava tijekom virusne infekcije
Title (english): The role of PrPC in the immune system upon exposure to viruses
Leader: Tihana Lenac Roviš
Jurisdiction: Croatia
Funding stream: Sveučilište u Rijeci
ProjectNumber: N/A
Title (croatian): Centar izvrsnosti za virusnu imunologiju i cjepiva
Title (english): Centre of Excellence for Research in Viral Immunology and the Development of New Vaccines
Acronym: CERVirVac
Leader: Stipan Jonjić
Jurisdiction: Croatia
Funding stream: ZCI
Document URLhttps://www.mdpi.com/1422-0067/22/10/5274
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-09-17 12:37:26