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Scientific paper - Chapter in Book
Dyslipidemia: Current Perspectives and Implications for Clinical Practice
In: Management of Dyslipidemia / Aronow, Wilbert S. (Ed.). Rijeka: IntechOpen, 2021. pp. 148-158. https://doi.org/10.5772/intechopen.87280
Klobučar Majanović, Sanja; Cvijanović Peloza, Olga; Detel, Dijana; Kenđel Jovanović, Gordana; Bakula, Miro; Rahelić, Dario; Čaljkušić-Mance, Tea; Šoić Vranić, Tamara; Zoričić Cvek, Sanja

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Klobučar Majanović, S., Cvijanović Peloza, O., Detel, D., Kenđel Jovanović, G., Bakula, M., Rahelić, D. ... Zoričić Cvek, S. (2021). Dyslipidemia: Current Perspectives and Implications for Clinical Practice. In W. S. Aronow, (Ed.), Management of Dyslipidemia (pp. 148-158). Rijeka: IntechOpen. doi: 10.5772/intechopen.87280

Klobučar Majanović, Sanja, et al. "Dyslipidemia: Current Perspectives and Implications for Clinical Practice." Management of Dyslipidemia, edited by Wilbert S. Aronow, IntechOpen, 2021, pp. 148-158. https://urn.nsk.hr/urn:nbn:hr:184:104768

Klobučar Majanović, Sanja, Olga Cvijanović Peloza, Dijana Detel, Gordana Kenđel Jovanović, Miro Bakula, Dario Rahelić, Tea Čaljkušić Mance, Tamara Šoić Vranić and Sanja Zoričić Cvek. "Dyslipidemia: Current Perspectives and Implications for Clinical Practice." In Management of Dyslipidemia, edited by Wilbert S. Aronow, 148-158. Rijeka: IntechOpen, 2021. https://urn.nsk.hr/urn:nbn:hr:184:104768

Klobučar Majanović, S., et al. (2021) 'Dyslipidemia: Current Perspectives and Implications for Clinical Practice' in Aronow, W. S. (ed.) Management of Dyslipidemia Rijeka: IntechOpen, pp. 148-158. Available at: https://urn.nsk.hr/urn:nbn:hr:184:104768 (Accessed 11 July 2024)

Klobučar Majanović S, Cvijanović Peloza O, Detel D, Kenđel Jovanović G, Bakula M, Rahelić D, and sur.. Dyslipidemia: Current Perspectives and Implications for Clinical Practice. In: W. S. Aronow, ed. Management of Dyslipidemia. Rijeka: IntechOpen; 2021. Pp. 148-158. [cited 2024 July 11] Available at: https://urn.nsk.hr/urn:nbn:hr:184:104768

S. Klobučar Majanović, et al., "Dyslipidemia: Current Perspectives and Implications for Clinical Practice", Management of Dyslipidemia, W. S. Aronow, Ed. Rijeka: IntechOpen, 2021, pp. 148-158. [Online] Available at: https://urn.nsk.hr/urn:nbn:hr:184:104768

Metadata
Title (english)Dyslipidemia: Current Perspectives and Implications for Clinical Practice
AuthorSanja Klobučar Majanović
AuthorOlga Cvijanović Peloza
AuthorDijana Detel
AuthorGordana Kenđel Jovanović
AuthorMiro Bakula
AuthorDario Rahelić
AuthorTea Čaljkušić-Mance
AuthorTamara Šoić Vranić
AuthorSanja Zoričić Cvek
EditorWilbert S. Aronow
Author's institutionUniversity of Rijeka
Faculty of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Dyslipidemia refers to a broad spectrum of various genetic and acquired disorders that affect blood lipid levels and largely contribute to global cardiovascular disease burden. Consistent evidence from epidemiological and clinical studies, supports the key role of the circulating LDL- cholesterol and other apoB containing lipoproteins in atherogenesis. All ApoB-containing lipoproteins with size less than 70 nm can cross the endothelial barrier, particularly in the presence of endothelial dysfunction. Uptake and accumulation of apoB-containing lipoproteins in the arterial wall is a critical initiating event in the development of atherosclerosis. Statin treatment, targeting LDL cholesterol reduction, remains the cornerstone of dyslipidemia management. There are abundant data supporting the concept of ‘the lower LDL-C, the better’ in the primary and secondary cardiovascular disease prevention. This chapter provides an overview of the key insights into the lipid abnormalities associated with an increased risk of CV events particulary in the context of dyslipidemia management in everyday clinical practice. Understanding the important role that metabolic derangements play in the pathogenesis of atherosclerosis pave the way for stronger implementation of current guidelines for CVD risk assessment and prevention.
Keywords (english)
Languageenglish
Publication typeScientific paper - Chapter in Book
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Book titleManagement of Dyslipidemia
Numberingpp. 148-158
ISBN978-1-83968-508-8
DOIhttps://doi.org/10.5772/intechopen.87280
URN:NBNurn:nbn:hr:184:104768
Publication2021
Document URLhttp://bib.irb.hr/1163204
Type of resourceText
PublisherIntechOpen
Publishing placeRijeka
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-01-04 13:50:37