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Scientific paper - Original scientific paper
Tianeptine in the combined treatment of combat related posttraumatic stress disorder
Psychiatria Danubina, 23 (2011), 3; 257-263. urn:nbn:hr:184:747411
Frančišković, Tanja; Šuković, Zoran; Janović, Sanja; Stevanović, Aleksandra; Nemčić Moro, Iva; Rončević Gržeta, Ika; Letica-Crepulja, Marina

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Frančišković, T., Šuković, Z., Janović, S., Stevanović, A., Nemčić Moro, I., Rončević Gržeta, I. & Letica Crepulja, M. (2011). Tianeptine in the combined treatment of combat related posttraumatic stress disorder. Psychiatria Danubina, 23. (3), 257-263. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:747411

Frančišković, Tanja, et al. "Tianeptine in the combined treatment of combat related posttraumatic stress disorder." Psychiatria Danubina, vol. 23, no. 3, 2011, pp. 257-263. https://urn.nsk.hr/urn:nbn:hr:184:747411

Frančišković, Tanja, Zoran Šuković, Sanja Janović, Aleksandra Stevanović, Iva Nemčić Moro, Ika Rončević Gržeta and Marina Letica Crepulja. "Tianeptine in the combined treatment of combat related posttraumatic stress disorder." Psychiatria Danubina 23, no. 3 (2011): 257-263. https://urn.nsk.hr/urn:nbn:hr:184:747411

Frančišković, T., et al. (2011) 'Tianeptine in the combined treatment of combat related posttraumatic stress disorder', Psychiatria Danubina, 23(3), pp. 257-263. Available at: https://urn.nsk.hr/urn:nbn:hr:184:747411 (Accessed 11 January 2025)

Frančišković T, Šuković Z, Janović S, Stevanović A, Nemčić Moro I, Rončević Gržeta I, and sur.. Tianeptine in the combined treatment of combat related posttraumatic stress disorder. Psychiatria Danubina [Internet]. 2011 [cited 2025 January 11];23(3):257-263. Available at: https://urn.nsk.hr/urn:nbn:hr:184:747411

T. Frančišković, et al., "Tianeptine in the combined treatment of combat related posttraumatic stress disorder", Psychiatria Danubina, vol. 23, no. 3, pp. 257-263, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:747411. [Accessed: 11 January 2025]

Metadata
Title (english)Tianeptine in the combined treatment of combat related posttraumatic stress disorder
Title (english)TIianeptine in the combined treatment of combat related posttraumatic stress disorder
AuthorTanja Frančišković
AuthorZoran Šuković
AuthorSanja Janović
AuthorAleksandra Stevanović
AuthorIva Nemčić Moro
AuthorIka Rončević Gržeta
AuthorMarina Letica-Crepulja
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Psychiatry and Psychological Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Psychiatry
Abstract (english)
The aim of this study was to evaluate the efficacy of tianeptine, an antidepressant that acts by increasing serotonin reuptake, in the treatment of posttraumatic stress disorder and to compare the effects of tianeptine and fluoxetine, an antidepressant from the selective serotonin reuptake inhibitors class. 43 war veterans suffering from posttraumatic stress disorder were included in the study. During the 5.5 months of treatment 21 patients were receiving tianeptine and 22 were receiving fluoxetine. In addition, all patients took part in intensive trauma specific group psychotherapy. The effects of the two antidepressants on symptoms of PTSD, depression and anxiety after 5.5 months of treatment were assessed using the Harvard Trauma Questionnaire, Beck Depression Inventory, STAI and the List of Drug Use and Side Effects. There was no significant difference between the two treatment groups regarding their effect on symptoms and severity of depression. The level of anxiety was the same in the first measurement but the difference became significant in other three measurements in favor of tianeptine. The anxiolytics and other co-prescribed drugs remain the same in both groups, the use of analgesics significantly increase in fluoxetine group during the course of treatment. The study demonstrated that tianeptine is as effective as fluoxetine in the treatment of PTSD, with even stronger effect on anxiety and equal tolerance.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titlePsychiatria Danubina
Numberingvol. 23, no. 3, pp. 257-263
p-ISSN0353-5053
URN:NBNurn:nbn:hr:184:747411
Publication2011
ProjectNumber: 130-1301422-1418
Title (croatian): Prilagodba pojedinca i zajednice u vrijeme društvene tranzicije
Title (english): Individual and community adjustment at times of social transition
Leader: Dean Ajduković
Jurisdiction: Croatia
Funding stream: ZP
Document URLhttp://bib.irb.hr/526685
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-02-01 14:20:50