prikaz prve stranice dokumenta An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia
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Scientific paper - Original scientific paper
An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia
Prostaglandins leukotrienes and essential fatty acids, 135 (2018); 139-141. urn:nbn:hr:184:472934
Nadalin, Sergej; Buretić-Tomljanović, Alena

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Nadalin, S. & Buretić Tomljanović, A. (2018). An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia. Prostaglandins leukotrienes and essential fatty acids, 135., 139-141. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:472934

Nadalin, Sergej and Alena Buretić Tomljanović. "An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia." Prostaglandins leukotrienes and essential fatty acids, vol. 135, 2018, pp. 139-141. https://urn.nsk.hr/urn:nbn:hr:184:472934

Nadalin, Sergej and Alena Buretić Tomljanović. "An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia." Prostaglandins leukotrienes and essential fatty acids 135 (2018): 139-141. https://urn.nsk.hr/urn:nbn:hr:184:472934

Nadalin, S. and Buretić Tomljanović, A. (2018) 'An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia', Prostaglandins leukotrienes and essential fatty acids, 135, pp. 139-141. Available at: https://urn.nsk.hr/urn:nbn:hr:184:472934 (Accessed 10 May 2024)

Nadalin S, Buretić Tomljanović A. An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia. Prostaglandins leukotrienes and essential fatty acids [Internet]. 2018 [cited 2024 May 10];135:139-141. Available at: https://urn.nsk.hr/urn:nbn:hr:184:472934

S. Nadalin and A. Buretić Tomljanović, "An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia", Prostaglandins leukotrienes and essential fatty acids, vol. 135, pp. 139-141, 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:472934. [Accessed: 10 May 2024]

Metadata
Title (english)An association between the BanI polymorphism of the PLA2G4A gene for calcium-dependent phospholipase A2 and plasma glucose levels among females with schizophrenia
AuthorSergej Nadalin
AuthorAlena Buretić-Tomljanović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract (english)
Abnormal glucose and lipid metabolism may be associated with altered cytosolic Ca2+-dependent phospholipase A2 (cPLA2) signaling in patients with schizophrenia. The relationship between schizophrenia and the functional BanI polymorphism (rs10798059 variant, A/G polymorphism) of the PLA2G4A gene for cPLA2 has been extensively investigated. We previously reported that it can influence several clinical features of schizophrenia, and it was shown to contribute to schizophrenia risk in several population studies. We performed PCR/RFLP genotyping of 263 Croatian patients (males/females: 139/124) to investigate the relationship between the BanI polymorphism and fasting plasma glucose and lipid levels in patients with schizophrenia. Our results indicate that the BanI polymorphic variant contributes significantly to plasma glucose levels in female patients. Females carrying the PLA2G4A-G allele (PLA2G4A-GG homozygous and PLA2G4A-AG heterozygous) presented with lower glucose levels than PLA2G4A-AA homozygous carriers, and the PLA2G4A genotype contributed approximately 6% of plasma glucose level variability in this group of patients.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleProstaglandins leukotrienes and essential fatty acids
Numberingvol. 135, pp. 139-141
p-ISSN0952-3278
URN:NBNurn:nbn:hr:184:472934
Publication2018
Document URLhttp://bib.irb.hr/949494
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-02-07 12:08:10