prikaz prve stranice dokumenta Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.
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Scientific paper - Original scientific paper
Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.
Breast, 31 (2017), 1; 16-19. https://doi.org/10.1016/j.breast.2016.10.018
Bošković, Lidija; Gašparić, Maja; Petković, Marija; Gugić, Damir; Belac-Lovasić, Ingrid; Soldić, Željko; Petrić Miše, Branka; Dabelić, Nina; Vazdar, Ljubica; Vrdoljak, Eduard

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Bošković, L., Gašparić, M., Petković, M., Gugić, D., Belac Lovasić, I., Soldić, Ž. ... Vrdoljak, E. (2017). Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.. Breast, 31. (1), 16-19. doi: 10.1016/j.breast.2016.10.018

Bošković, Lidija, et al. "Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.." Breast, vol. 31, no. 1, 2017, pp. 16-19. https://doi.org/10.1016/j.breast.2016.10.018

Bošković, Lidija, Maja Gašparić, Marija Petković, Damir Gugić, Ingrid Belac Lovasić, Željko Soldić, Branka Petrić Miše, Nina Dabelić, Ljubica Vazdar and Eduard Vrdoljak. "Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.." Breast 31, no. 1 (2017): 16-19. https://doi.org/10.1016/j.breast.2016.10.018

Bošković, L., et al. (2017) 'Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.', Breast, 31(1), pp. 16-19. doi: 10.1016/j.breast.2016.10.018

Bošković L, Gašparić M, Petković M, Gugić D, Belac Lovasić I, Soldić Ž, and sur.. Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.. Breast [Internet]. 2017 [cited 2024 May 14];31(1):16-19. doi: 10.1016/j.breast.2016.10.018

L. Bošković, et al., "Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.", Breast, vol. 31, no. 1, pp. 16-19, 2017. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:731047. [Accessed: 14 May 2024]

Metadata
Title (english)Bone health and adherence to vitamin D and calcium therapy in early breast cancer patients on endocrine therapy with aromatase inhibitors.
AuthorLidija Bošković
AuthorMaja Gašparić
AuthorMarija Petković
AuthorDamir Gugić
AuthorIngrid Belac-Lovasić
AuthorŽeljko Soldić
AuthorBranka Petrić Miše
AuthorNina Dabelić
AuthorLjubica Vazdar
AuthorEduard Vrdoljak
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Oncology and Radiotherapy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
OBJECTIVES: Randomized trials involving aromatase inhibitors (AIs) in the adjuvant treatment of breast cancer patients have reported increased osteoporosis risk. Bone loss can be reduced with appropriate life style, vitamin D and calcium supplements, and with bisphosphonate therapy. The aim of this analysis was to investigate adherence to vitamin D and calcium in postmenopausal breast cancer patients receiving adjuvant non-steroidal AIs, and oncologists' adherence to the bone health guidelines. MATERIAL AND METHODS: This prospective study included 438 newly diagnosed patients and those who have already been receiving non-steroidal AIs for up to 3.5 years. Median endocrine therapy duration before recruitment in the study was 10.5 months (interquartile 4.8-26.6). RESULTS: Densitometry was performed on 142 patients (32.4%) before initiation of endocrine therapy, and on additional 38 (8.6%) patients at second study visit. Densitometry was not performed on 258 (59%) patients. Vitamin D and calcium were prescribed to 329/438 (75.1%) patients at some point during the study. Patients who took more than 80% of the prescribed dose were considered adherent. Self-reported adherence was 88.4%. Osteoporosis was diagnosed in 24 patients (5.5%) of the total study population, bearing in mind that 258/438 (59%) patients did not have densitometry. Bisphosphonates were prescribed to 54/438 (12.3%) patients, whilst only 19 (35.2%) of those had osteoporosis. CONCLUSION: In this analysis, lack of oncologists' adherence to the bone health guidelines was observed. In addition, a significant proportion of the patients did not adhere to the vitamin D and calcium.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBreast
Numberingvol. 31, no. 1, pp. 16-19
p-ISSN0960-9776
DOIhttps://doi.org/10.1016/j.breast.2016.10.018
URN:NBNurn:nbn:hr:184:731047
Publication2017
Document URLhttp://bib.irb.hr/999245
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-02-08 14:01:43