prikaz prve stranice dokumenta CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential
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Scientific paper - Original scientific paper
CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential
Anticancer Research, 36 (2016), 10; 5437-5442. urn:nbn:hr:184:172976
Bišćanin, Alen; Ljubičić, Neven; Boban, Marko; Baličević, Drinko; Pavić, Ivana; Maver-Bišćanin, Mirela; Budimir, Ivan; Dorošulić, Zdravko; Duvnjak, Marko

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Bišćanin, A., Ljubičić, N., Boban, M., Baličević, D., Pavić, I., Maver Bišćanin, M. ... Duvnjak, M. (2016). CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential. Anticancer Research, 36. (10), 5437-5442. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:172976

Bišćanin, Alen, et al. "CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential." Anticancer Research, vol. 36, no. 10, 2016, pp. 5437-5442. https://urn.nsk.hr/urn:nbn:hr:184:172976

Bišćanin, Alen, Neven Ljubičić, Marko Boban, Drinko Baličević, Ivana Pavić, Mirela Maver Bišćanin, Ivan Budimir, Zdravko Dorošulić and Marko Duvnjak. "CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential." Anticancer Research 36, no. 10 (2016): 5437-5442. https://urn.nsk.hr/urn:nbn:hr:184:172976

Bišćanin, A., et al. (2016) 'CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential', Anticancer Research, 36(10), pp. 5437-5442. Available at: https://urn.nsk.hr/urn:nbn:hr:184:172976 (Accessed 30 November 2024)

Bišćanin A, Ljubičić N, Boban M, Baličević D, Pavić I, Maver Bišćanin M, and sur.. CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential. Anticancer Research [Internet]. 2016 [cited 2024 November 30];36(10):5437-5442. Available at: https://urn.nsk.hr/urn:nbn:hr:184:172976

A. Bišćanin, et al., "CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential", Anticancer Research, vol. 36, no. 10, pp. 5437-5442, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:172976. [Accessed: 30 November 2024]

Metadata
Title (english)CX43 Expression in Colonic Adenomas and Surrounding Mucosa Is a Marker of Malignant Potential
AuthorAlen Bišćanin
MBZ: 351974
AuthorNeven Ljubičić
MBZ: 164614
AuthorMarko Boban
AuthorDrinko Baličević
MBZ: 149553
AuthorIvana Pavić
AuthorMirela Maver-Bišćanin
MBZ: 281004
AuthorIvan Budimir
AuthorZdravko Dorošulić
AuthorMarko Duvnjak
MBZ: 138233
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Colorectal cancer is a major public health problem. The adenoma-carcinoma sequence offers potential for screening and surveillance. We tested the clinical behavior and diagnostic utility of connexin 43 (CX43) in connection with pathohistological risk. Immunohistochemical expression of CX43 in colonic adenomas and surrounding mucosa from 87 patients was determined. CX43 expression was higher in mucosa surrounding adenomas with high-grade dysplasia (p=0.047), larger adenomas (p=0.015) and villous adenomas (p=0.02). No difference of CX43 expression in adenomas according to grade of dysplasia was found (p=0.87). CX43 expression in adenomas was dependent on the patient's hemoglobin level (p=0.002), family history of colorectal cancer (p=0.009) and statin therapy (p=0.049). CX43 expression in mucosa surrounding adenoma could be an additional factor indicative of malignant potential. CX43 expression in colonic adenoma seems to be closely related to family history of colorectal cancer, statin therapy and hemoglobin level.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleAnticancer Research
Numberingvol. 36, no. 10, pp. 5437-5442
p-ISSN0250-7005
e-ISSN1791-7530
URN:NBNurn:nbn:hr:184:172976
Publication2016
Document URLhttp://bib.irb.hr/917130
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-02-15 10:56:20