prikaz prve stranice dokumenta Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?
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Scientific paper - Original scientific paper
Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?
Medical Hypotheses, 96 (2016); 16-19. https://doi.org/10.1016/j.mehy.2016.09.017
Čubranić, Aleksandar; Dobrila-Dintinjana, Renata; Redžović, Arnela; Dintinjana, Marijan; Petranović, Duška; Golčić, Marin

Institutional repository: Repository of the University of Rijeka, Faculty of Medicine

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Čubranić, A., Dobrila Dintinjana, R., Redžović, A., Dintinjana, M., Petranović, D. & Golčić, M. (2016). Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?. Medical Hypotheses, 96., 16-19. doi: 10.1016/j.mehy.2016.09.017

Čubranić, Aleksandar, et al. "Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?." Medical Hypotheses, vol. 96, 2016, pp. 16-19. https://doi.org/10.1016/j.mehy.2016.09.017

Čubranić, Aleksandar, Renata Dobrila Dintinjana, Arnela Redžović, Marijan Dintinjana, Duška Petranović and Marin Golčić. "Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?." Medical Hypotheses 96 (2016): 16-19. https://doi.org/10.1016/j.mehy.2016.09.017

Čubranić, A., et al. (2016) 'Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?', Medical Hypotheses, 96, pp. 16-19. doi: 10.1016/j.mehy.2016.09.017

Čubranić A, Dobrila Dintinjana R, Redžović A, Dintinjana M, Petranović D, Golčić M. Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?. Medical Hypotheses [Internet]. 2016 [cited 2024 April 23];96:16-19. doi: 10.1016/j.mehy.2016.09.017

A. Čubranić, R. Dobrila Dintinjana, A. Redžović, M. Dintinjana, D. Petranović and M. Golčić, "Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?", Medical Hypotheses, vol. 96, pp. 16-19, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:939699. [Accessed: 23 April 2024]

Metadata
Title (english)Endogenous erythropoietin and erythropoietin receptors in colorectal cancer ; can we answer the questions?
AuthorAleksandar Čubranić
AuthorRenata Dobrila-Dintinjana
AuthorArnela Redžović
AuthorMarijan Dintinjana
AuthorDuška Petranović
AuthorMarin Golčić https://orcid.org/0000-0002-3388-4813
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Oncology and Radiotherapy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Erythropoietin (Epo) is glycoprotein hormone which binds on erythropoietin receptors (EpoR) promoting proliferation and differentiation. Studies have shown that EpoR, apart from erythrocyte precursors, is expressed on no hematopoietic tissue and various tumor cells. Despite the progress in modern medicine, colorectal carcinoma (CRC) is still the leading cause of increased morbidity and mortality between oncology patients worldwide. Its precursors are benign villous adenomas, which in certain percentage progress to cancer. Anemia of chronic disease is common finding in CRC patients. Some of them are treated with Epo. Epo/EpoR seems to correlate with tumor progression and metastasizing. Therefore, the identification of at-risk group remains a clinical challenge. Vascular endothelial growth factor (VEGF) is a signal protein that stimulates angiogenesis and concentration of VEGF is positive correlated with tumor growth in numerous tumors. The importance of Epo in tumor pathogenesis has led to a growing interest in the potential prognostic value. By our point of view there are many open questions about role of Epo/EpoR in CRC.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedical Hypotheses
Numberingvol. 96, pp. 16-19
p-ISSN0306-9877
DOIhttps://doi.org/10.1016/j.mehy.2016.09.017
URN:NBNurn:nbn:hr:184:939699
Publication2016
Document URLhttp://bib.irb.hr/998007
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-02-18 09:40:52