Introduction: HELLP syndrome is characterized by hemolysis, elevated liver enzymes and low platelet count. It’s a serious complication in pregnancy which occurs in 0.2 to 0.8% of all pregnancies and often follows severe preeclampsia. According to the current Mississippi classification HELLP syndrome is divided into three stages depending on the severity of the clinical presentation. Also, it carries a high risk of adverse perinatal outcomes. This article describes incidence, diagnosis, maternal risk factors and comorbidities, mode of delivery, gestational age and Apgar score of the fetus. Purpose: The purpose of this study was to determine the course and outcome of pregnancies with HELLP syndrome in women received at the Department of Obstetrics and Gynecology, Clinical Hospital Center Rijeka, during the period from 1 January 2005 to 31 December 2014. Patients and methods: We analyzed a group of 25 pregnant women, based on data collected from the Register of Clinical Hospital Center Rijeka. Microsoft Excel was used for analysis. Results: HELLP syndrome manifested itself in 25 pregnant women in the period from 1 January 2005 to 31 December 2014, with the largest number of cases and the highest incidence in year 2010. HELLP syndrome represented the most in nulliparous single pregnancies, in pregnant women aged from 31 to 35 years and natural pregnancies. Most pregnant women had an ideal BMI before pregnancy and had no recorded hypertensive disorder. The most frequently mentioned symptoms in hospitalization were high blood pressure, epigastric pain or pain in the right upper abdominal quadrant and headache. The most common comorbidities were preeclampsia, IUGR and chronic placental insufficiency. HELLP syndrome pregnancies were usually completed by caesarean section. The gestational age of newborns was <37 weeks in 80% and the investigated Apgar score in the first minute was <7 in 37% of infants while in the 5th minute it remained <7 in 22% of infants. In 76% of pregnant women HELLP syndrome presented itself with mild laboratory abnormalities. There was no statistically significant difference in examining the relationship between the stages of HELLP syndrome and the parameters above : maternal age, BMI before pregnancy and gestational age of the child. Conclusion: In this retrospective analysis, it has been proven that HELLP syndrome complicates pregnancy, childbirth and the puerperium, but his diagnosis and early termination of pregnancy lead to good perinatal outcomes in children of mothers with HELLP syndrome. Despite numerous literature that talks about HELLP syndrome there is a need to do further research on this topic.